Pasquini E, Rastelli E, Muretto P, Bonci A, Fattori P P, Nicolini M, Ravaioli A, Pasini P
Divisione di Oncologia, Ospedale Infermi, Rimini.
Pathologica. 1994 Oct;86(5):546-8.
A case of primary bronchial malignant melanoma occurred in a 66 years old woman is reported. Because of cough and hemoptysis bronchoscopic examination was performed and and a polypoid mass was found to occlude the right lower bronchus. Histopathologic examination showed the presence of malignant melanoma also confirmed by immuno reactivity with antibodies to S-100 protein and melanoma associated monoclonal antibody HMB45. Clinical history, physical examination and other instrumental investigations failed to find other possible primary sites of the tumour. Primary melanoma of the lung is a very rare condition, but our case seems to satisfy the criteria to be considered in the little group of definite primary melanoma of the lower respiratory tract.
报告了一例发生在一名66岁女性身上的原发性支气管恶性黑色素瘤。因咳嗽和咯血进行了支气管镜检查，发现一个息肉样肿物阻塞右下支气管。组织病理学检查显示存在恶性黑色素瘤，用抗S-100蛋白抗体和黑色素瘤相关单克隆抗体HMB45的免疫反应性也证实了这一点。临床病史、体格检查和其他器械检查均未发现该肿瘤其他可能的原发部位。原发性肺黑色素瘤是一种非常罕见的疾病，但我们的病例似乎符合在少数明确的下呼吸道原发性黑色素瘤病例组中考虑的标准。
