Schneider Stefan, Guardiera Simon, Kleinert Jens, Steinbacher Anja, Abel Thomas, Carnahan Heather, Strüder Heiko K
Department of Exercise Neuroscience, Institute of Motor Control and Movement Technique, German Sport University Cologne, Cologne, Germany.
Stress. 2008 Sep;11(5):339-47. doi: 10.1080/10253890701802743.
It has been suggested that the central and peripheral neural processes (CPNP) are affected by gravitational changes. Based on the previous experiments during parabolic flights, central and peripheral changes may not only be due to the changed gravitational forces but also due to neuroendocrine reactions related to the psycho-physiological consequences of gravitational changes. The present study focuses on the interaction of neuroendocrine changes and the physical and mental states after acceleration to three-time terrestrial gravity (3Gz). Eleven participants (29.4+/-5.1 [SD] years (male (n=8): 30+/-5.1 years; female (n=3): 27.7+/-2.1 years) underwent a 15 min acceleration to 3Gz in a human centrifuge. Before and after the acceleration to 3Gz circulating stress hormone concentrations (cortisol, adrenocorticotropic hormone (ACTH), prolactin, epinephrine, norepinephrine) and perceived physical and mental states were recorded. A second control group of 11 participants underwent the same testing procedure in a laboratory session. Serum cortisol concentration during exposure to the centrifugal acceleration increased by 70%, plasma concentration of ACTH increased threefold, prolactin twofold, epinephrine by 70% and norepinephrine by 45%, whereas the perceived physical well-being decreased. These findings demonstrate that psycho-physiological changes have to be regarded as a relevant factor for the changes in CPNP during phases of hypergravity exposure.
有人提出，中枢和外周神经过程（CPNP）会受到重力变化的影响。基于之前在抛物线飞行期间进行的实验，中枢和外周的变化可能不仅归因于重力的改变，还归因于与重力变化的心理生理后果相关的神经内分泌反应。本研究聚焦于加速至三倍地球重力（3Gz）后神经内分泌变化与身心状态之间的相互作用。11名参与者（年龄29.4±5.1[标准差]岁（男性（n = 8）：30±5.1岁；女性（n = 3）：27.7±2.1岁）在人体离心机中经历了15分钟加速至3Gz的过程。在加速至3Gz之前和之后，记录循环应激激素浓度（皮质醇、促肾上腺皮质激素（ACTH）、催乳素、肾上腺素、去甲肾上腺素）以及感知到的身心状态。另一组由11名参与者组成的对照组在实验室环节中接受相同的测试程序。在离心加速过程中，血清皮质醇浓度增加了70%，ACTH的血浆浓度增加了三倍，催乳素增加了两倍，肾上腺素增加了70%，去甲肾上腺素增加了45%，而感知到的身体幸福感下降。这些发现表明，在超重力暴露阶段，心理生理变化必须被视为CPNP变化的一个相关因素。
