Takeyama Junji, Ando Ryo, Sato Tomoyuki, Nio Masaki, Shimanuki Yoshihisa, Sato Atsushi, Imaizumi Masue
Department of Pathology, Miyagi Children's Hospital, Sendai, Japan.
Pathol Int. 2008 Sep;58(9):606-8. doi: 10.1111/j.1440-1827.2008.02277.x.
Described herein is the case of an 8-year-old boy who developed a hepatic nodular lesion after having received anti-neoplastic therapy for nephroblastoma. Histological examination of the excised specimen indicated a disordered arrangement of hepatic components with hemangioma-like features. This case was diagnosed as a variant of focal nodular hyperplasia. It is speculated that this hepatic lesion is a late complication of treatment for nephroblastoma and might develop from congenital malformative area of the liver.
本文描述了一名8岁男孩的病例,该男孩在接受肾母细胞瘤抗肿瘤治疗后出现肝脏结节性病变。对切除标本的组织学检查显示肝脏成分排列紊乱,具有血管瘤样特征。该病例被诊断为局灶性结节性增生的一种变体。推测这种肝脏病变是肾母细胞瘤治疗的晚期并发症,可能起源于肝脏的先天性畸形区域。