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一名曾接受肾母细胞瘤治疗的儿童肝脏出现局灶性结节性增生样病变。

Focal nodular hyperplasia-like lesion of the liver in a child previously treated for nephroblastoma.

作者信息

Takeyama Junji, Ando Ryo, Sato Tomoyuki, Nio Masaki, Shimanuki Yoshihisa, Sato Atsushi, Imaizumi Masue

机构信息

Department of Pathology, Miyagi Children's Hospital, Sendai, Japan.

出版信息

Pathol Int. 2008 Sep;58(9):606-8. doi: 10.1111/j.1440-1827.2008.02277.x.

Abstract

Described herein is the case of an 8-year-old boy who developed a hepatic nodular lesion after having received anti-neoplastic therapy for nephroblastoma. Histological examination of the excised specimen indicated a disordered arrangement of hepatic components with hemangioma-like features. This case was diagnosed as a variant of focal nodular hyperplasia. It is speculated that this hepatic lesion is a late complication of treatment for nephroblastoma and might develop from congenital malformative area of the liver.

摘要

本文描述了一名8岁男孩的病例,该男孩在接受肾母细胞瘤抗肿瘤治疗后出现肝脏结节性病变。对切除标本的组织学检查显示肝脏成分排列紊乱,具有血管瘤样特征。该病例被诊断为局灶性结节性增生的一种变体。推测这种肝脏病变是肾母细胞瘤治疗的晚期并发症,可能起源于肝脏的先天性畸形区域。

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