Grøndahl Jan Robert, Rosvold Elin Olaug
Institute of General Practice and Community Medicine, Faculty of Medicine, University of Oslo, Norway.
BMC Musculoskelet Disord. 2008 Sep 18;9:124. doi: 10.1186/1471-2474-9-124.
Hypnosis treatment in general practice is a rather new concept. This pilot study was performed to evaluate the effect of a standardized hypnosis treatment used in general practice for patients with chronic widespread pain (CWP).
The study was designed as a randomized control group-controlled study. Sixteen patients were randomized into a treatment group or a control group, each constituting eight patients. Seven patients in the treatment group completed the schedule. After the control period, five of the patients in the control group also received treatment, making a total of 12 patients having completed the treatment sessions. The intervention group went through a standardized hypnosis treatment with ten consecutive therapeutic sessions once a week, each lasting for about 30 minutes, focusing on ego-strengthening, relaxation, releasing muscular tension and increasing self-efficacy. A questionnaire was developed in order to calibrate the symptoms before and after the 10 weeks period, and the results were interpolated into a scale from 0 to 100, increasing numbers representing increasing suffering. Data were analyzed by means of T-tests.
The treatment group improved from their symptoms, (change from 62.5 to 55.4), while the control group deteriorated, (change from 37.2 to 45.1), (p = 0,045). The 12 patients who completed the treatment showed a mean improvement from 51.5 to 41.6. (p = 0,046). One year later the corresponding result was 41.3, indicating a persisting improvement.
The study indicates that hypnosis treatment may have a positive effect on pain and quality of life for patients with chronic muscular pain. Considering the limited number of patients, more studies should be conducted to confirm the results.
The study was registered in ClinicalTrials.gov and released 27.08.07 Reg nr NCT00521807 Approval Number: 05032001.
全科医疗中的催眠治疗是一个相当新的概念。本试点研究旨在评估全科医疗中使用的标准化催眠治疗对慢性广泛性疼痛（CWP）患者的效果。
该研究设计为随机对照试验。16名患者被随机分为治疗组或对照组，每组8名患者。治疗组中有7名患者完成了疗程。在对照期结束后，对照组中的5名患者也接受了治疗，共有12名患者完成了治疗疗程。干预组接受了标准化的催眠治疗，每周连续进行10次治疗，每次持续约30分钟，重点是增强自我、放松、缓解肌肉紧张和提高自我效能感。为了校准10周前后的症状，开发了一份问卷，结果被换算成0至100的量表，数值越高表示痛苦程度越高。数据采用t检验进行分析。
治疗组症状有所改善（从62.5降至55.4），而对照组症状恶化（从37.2升至45.1），（p = 0.045）。完成治疗的12名患者平均改善情况为从51.5降至41.6。（p = 0.046）。一年后相应结果为41.3，表明改善持续存在。
该研究表明催眠治疗可能对慢性肌肉疼痛患者的疼痛和生活质量有积极影响。鉴于患者数量有限，应进行更多研究以证实结果。
该研究已在ClinicalTrials.gov注册，并于2007年8月27日发布，注册号为NCT00521807，批准号：05032001。
