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疼痛的神经生理学和慢性疼痛的催眠。

Neurophysiology of pain and hypnosis for chronic pain.

机构信息

Department of Psychiatry & Behavioral Sciences, University of Washington, Box 354944, Seattle, WA 98195 USA.

出版信息

Transl Behav Med. 2012 Mar;2(1):65-72. doi: 10.1007/s13142-011-0084-5.

DOI:10.1007/s13142-011-0084-5
PMID:24073099
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3717822/
Abstract

In the past decade there has been a dramatic increase in (1) understanding the neurophysiological components of the pain experiences, (2) randomized clinical trials testing the efficacy of hypnotic treatments on chronic pain, and (3) laboratory research examining the effects of hypnosis on the neurophysiological processes implicated in pain. Work done in these areas has not only demonstrated the efficacy of hypnosis for treating chronic pain but is beginning to shed light on neurophysiological processes that may play a role in its effectiveness. This paper reviews a selection of published studies from these areas of research, focusing on recent findings that have the most potential to inform both clinical work and research in this area. The paper concludes with research and clinical recommendations for maximizing treatment efficacy based on the research findings that are available.

摘要

在过去的十年中,人们对(1)疼痛体验的神经生理成分的理解、(2)催眠治疗慢性疼痛的随机临床试验、(3)实验室研究中催眠对疼痛相关神经生理过程的影响有了显著的认识。这些领域的工作不仅证明了催眠治疗慢性疼痛的疗效,而且开始揭示可能对其有效性起作用的神经生理过程。本文综述了这些研究领域的部分已发表研究,重点介绍了最有潜力为这一领域的临床工作和研究提供信息的最新发现。本文最后根据现有研究结果,就如何最大限度地提高治疗效果提出了研究和临床建议。

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[Pharmacological treatment of chronic pain].[慢性疼痛的药物治疗]
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Long-term pain, stiffness, and functional disability after total knee arthroplasty with and without an extended ambulatory continuous femoral nerve block: a prospective, 1-year follow-up of a multicenter, randomized, triple-masked, placebo-controlled trial.全膝关节置换术后长期疼痛、僵硬和功能障碍,伴有或不伴有延长的门诊连续股神经阻滞:一项多中心、随机、三盲、安慰剂对照试验的 1 年前瞻性随访。
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