Singh I S, Jaiswal D D, Nair Suma, Vijayagopal P, Bhati S, Garg S P
Internal Dosimetry Division, Bhabha Atomic Research Centre, BARC Hospital, Mumbai 400 0094, India.
Radiat Prot Dosimetry. 2008;131(4):425-30. doi: 10.1093/rpd/ncn245. Epub 2008 Sep 17.
The daily intake of natural uranium and its contents in the lungs, skeleton, liver and kidney of an Indian adult population group was estimated using radiochemical neutron activation analysis (RNAA). These data on daily intake (through inhalation and ingestion) were used to compute the uranium contents in the lungs and other systemic organs such as the skeleton, liver and kidney, using the new human respiratory tract model (HRTM) and the new biokinetic model of uranium. The theoretically computed uranium contents in the lungs, skeleton, liver and kidney of an average Indian adult are 1.16, 1.96, 0.07 and 0.04 microg, respectively, and the corresponding experimentally measured values are 1.23 (1.76), 2.92 (2.5), 0.07 (1.76) and 0.19 (1.47) microg in an urban population group living in Mumbai. The values given in parentheses are geometric standard deviation (GSD). It is seen that the measured uranium contents in the lungs, skeleton and liver agree very well with the corresponding computed values, but the measured value for the kidney is observed to be on the higher side of the computed value. However, in view of many uncertainties, the overall agreement between the measured and the computed values can be considered to be good. Therefore, the result from this study can be taken as a validation of the new biokinetic model of uranium in Indian conditions.
采用放射化学中子活化分析（RNAA）估算了印度成年人群体中天然铀的每日摄入量及其在肺部、骨骼、肝脏和肾脏中的含量。利用新的人类呼吸道模型（HRTM）和铀的新生物动力学模型，将这些关于每日摄入量（通过吸入和摄入）的数据用于计算肺部以及骨骼、肝脏和肾脏等其他全身器官中的铀含量。印度成年男性肺部、骨骼、肝脏和肾脏中理论计算出的铀含量分别为1.16、1.96、0.07和0.04微克，而在居住于孟买的城市人群体中，相应的实验测量值分别为1.23（1.76）、2.92（2.5）、0.07（1.76）和0.19（1.47）微克。括号内给出的值为几何标准差（GSD）。可以看出，肺部、骨骼和肝脏中测量的铀含量与相应的计算值非常吻合，但观察到肾脏的测量值高于计算值。然而，鉴于存在许多不确定性，可以认为测量值与计算值之间的总体一致性良好。因此，本研究结果可作为印度条件下铀新生物动力学模型的验证。
