Hardy Billie-Jo, Séguin Béatrice, Singer Peter A, Mukerji Mitali, Brahmachari Samir K, Daar Abdallah S
McLaughlin-Rotman Centre for Global Health, Program on Life Sciences, Ethics and Policy, University Health Network and University of Toronto, MaRS Centre, South Tower, Suite 406, 101 College Street, Toronto, Ontario M5G 1L7, Canada.
Nat Rev Genet. 2008 Oct;9 Suppl 1:S9-14. doi: 10.1038/nrg2440.
India currently has the world's second-largest population along with a fast-growing economy and significant economic disparity. It also continues to experience a high rate of infectious disease and increasingly higher rates of chronic diseases. However, India cannot afford to import expensive technologies and therapeutics nor can it, as an emerging economy, emulate the health-delivery systems of the developed world. Instead, to address these challenges it is looking to biotechnology-based innovation in the field of genomics. The Indian Genome Variation (IGV) consortium, a government-funded collaborative network among seven local institutions, is a reflection of these efforts. The IGV has recently developed the first large-scale database of genomic diversity in the Indian population that will facilitate research on disease predisposition, adverse drug reactions and population migration.
印度目前拥有世界第二大人口,经济快速增长且经济差距显著。该国还持续面临着高传染病发病率以及日益攀升的慢性病发病率。然而,印度既无力进口昂贵的技术和治疗手段,作为一个新兴经济体,也无法效仿发达国家的医疗服务体系。相反,为应对这些挑战,印度寄希望于基因组学领域基于生物技术的创新。印度基因组变异(IGV)联盟是由七个当地机构组成的政府资助合作网络,它正是这些努力的体现。IGV最近开发了首个印度人群基因组多样性大规模数据库,这将有助于开展疾病易感性、药物不良反应和人口迁移方面的研究。