接受体外受精或卵胞浆内单精子注射治疗的不孕夫妇的健康相关生活质量。
Health-related quality of life in infertile couples receiving IVF or ICSI treatment.
作者信息
Rashidi Batool, Montazeri Ali, Ramezanzadeh Fatemeh, Shariat Mamak, Abedinia Nasrin, Ashrafi Mahnaz
机构信息
Vali-e-Asr Reproductive Health Research Center, Tehran University of Medical Sciences, Tehran, Iran.
出版信息
BMC Health Serv Res. 2008 Sep 19;8:186. doi: 10.1186/1472-6963-8-186.
BACKGROUND
Infertile couples might experience psychological distress and suffer from impaired health-related quality of life. This study aimed to examine health-related quality of life in infertile couples receiving either in-vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) treatment.
METHODS
This was a cross-sectional study of quality of life in infertile couples attending to Vali-e-Asr Reproductive Health Research Center or Royan Institute for either IVF or ICSI treatment in Tehran, Iran. Health-related quality of life was assessed using the Short Form Health Survey (SF-36). Patients' demographic and clinical characteristics were also recorded. Data were analyzed to compare quality of life in infertile women and men and to indicate what variables predict quality of life in infertile couples.
RESULTS
In all 514 women and 514 men (n = 1028) were studied. There were significant differences between women and men indicating that male patients had a better health-related quality of life. Also health-related quality of life was found to be better in infertility due to male factor. Performing logistic regression analysis it was found that female gender, and lower educational level were significant predictors of poorer physical health-related quality of life. For mental health-related quality of life in addition to female gender and lower educational level, younger age also was found to be a significant predictor of poorer condition. No significant results were observed for infertility duration or causes of infertility either for physical or mental health-related quality of life.
CONCLUSION
The findings suggest that infertility duration or causes of infertility do not have significant effects on health-related quality of life in infertile couples. However, infertile couples, especially less educated younger women, are at risk of a sub-optimal health-related quality of life and they should be provided help and support in order to improve their health-related quality of life.
背景
不孕夫妇可能会经历心理困扰，并遭受健康相关生活质量受损的痛苦。本研究旨在调查接受体外受精（IVF）或卵胞浆内单精子注射（ICSI）治疗的不孕夫妇的健康相关生活质量。
方法
这是一项横断面研究，对象是在伊朗德黑兰的瓦利 - 阿斯尔生殖健康研究中心或罗扬研究所接受IVF或ICSI治疗的不孕夫妇的生活质量。使用简短健康调查问卷（SF - 36）评估健康相关生活质量。还记录了患者的人口统计学和临床特征。对数据进行分析，以比较不孕女性和男性的生活质量，并指出哪些变量可预测不孕夫妇的生活质量。
结果
共研究了514名女性和514名男性（n = 1028）。女性和男性之间存在显著差异，表明男性患者的健康相关生活质量更好。此外，发现男性因素导致的不孕患者的健康相关生活质量更好。进行逻辑回归分析发现，女性性别和较低的教育水平是身体健康相关生活质量较差的显著预测因素。对于心理健康相关生活质量，除了女性性别和较低的教育水平外，年龄较小也是状况较差的显著预测因素。对于身体健康或心理健康相关生活质量，未观察到不孕持续时间或不孕原因有显著影响。
结论
研究结果表明，不孕持续时间或不孕原因对不孕夫妇的健康相关生活质量没有显著影响。然而，不孕夫妇，尤其是受教育程度较低的年轻女性，存在健康相关生活质量欠佳的风险，应为他们提供帮助和支持，以改善其健康相关生活质量。
Zotero 插件