Yazd Institute for Reproductive Sciences, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Eur J Obstet Gynecol Reprod Biol. 2012 Mar;161(1):38-41. doi: 10.1016/j.ejogrb.2011.11.025. Epub 2011 Dec 3.
Assisted reproductive technology (ART) has become an established and increasingly successful form of treatment for infertility. However, significant numbers of cycles fail after embryo transfer (ET) and it becomes necessary to follow up the infertile couples after failed ART treatments. The main goal was to follow up the infertile patients after failed IVF/ICSI+ET treatments in Iran and Turkey.
198 infertile couples from Iran and 355 infertile couples from Turkey were followed up after IVF/ICSI failures. The patients' demographic data, the couples' decisions about continuation of treatment and the spontaneous pregnancy rates were compared in the two countries.
The drop-out rate was higher in Iran (28.3%) than in Turkey (23.4%). The reasons for treatment discontinuation in Iran and Turkey were: financial problem (33.9% vs. 41%), hopeless (10.7% vs. 22.9%), fear of drug side-effects (7.1% vs. 12%), achieving pregnancy (37.5% vs. 19.6%), child adoption (5.4% vs. 2.4%), lack of spouse cooperation (5.4% vs. 2.4%), and divorce (0% vs. 2.4%). Spontaneous pregnancy was significantly higher in Iran (10.1%) than in Turkey (3.9%). There was correlation between duration of infertility and female factor infertility with spontaneous pregnancy.
Since the majority of couples that discontinued treatment had financial problems, it is essential for health professionals to support infertile couples during their childlessness crisis.
辅助生殖技术（ART）已成为治疗不孕不育症的一种成熟且日益成功的方法。然而，大量胚胎移植（ET）后周期失败，因此有必要对ART 治疗失败的不孕夫妇进行随访。主要目的是对伊朗和土耳其的 IVF/ICSI+ET 治疗失败后的不孕患者进行随访。
对伊朗的 198 对不孕夫妇和土耳其的 355 对不孕夫妇进行了 IVF/ICSI 失败后的随访。比较了两国患者的人口统计学数据、夫妇对继续治疗的决定以及自然妊娠率。
伊朗的失访率（28.3%）高于土耳其（23.4%）。伊朗和土耳其停止治疗的原因分别为：经济问题（33.9% vs. 41%）、绝望（10.7% vs. 22.9%）、担心药物副作用（7.1% vs. 12%）、已怀孕（37.5% vs. 19.6%）、收养孩子（5.4% vs. 2.4%）、配偶缺乏合作（5.4% vs. 2.4%）、离婚（0% vs. 2.4%）。伊朗的自然妊娠率明显高于土耳其（10.1% vs. 3.9%）。不孕时间和女性因素不孕与自然妊娠呈正相关。
由于大多数停止治疗的夫妇都存在经济问题，因此卫生专业人员在不孕夫妇面临无子危机时必须为他们提供支持。
