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不育症、精神障碍与幸福感——一项全国性调查。

Infertility, mental disorders and well-being--a nationwide survey.

机构信息

National Institute for Health and Welfare (THL), Child and Adolescent Health and Wellbeing Unit, Helsinki, Finland.

出版信息

Acta Obstet Gynecol Scand. 2010 May;89(5):677-82. doi: 10.3109/00016341003623746.

Abstract

OBJECTIVE

Earlier studies suggest that infertility and mental health problems are related and that infertility is a different experience for women and men. The aim of this population-based study is to examine mental disorders, depressivity, psychological distress, perceived health and quality of life among women and men who have experienced infertility.

DESIGN

Cross-sectional nationwide Health 2000 Survey.

SETTING

Population-based.

POPULATION

A representative random sample of Finnish people aged 30-44 years (n = 2291).

METHODS

Outcomes were compared between those who had experienced infertility (n = 338) and the rest of the population. Age, marital status, education, income, body mass index, and smoking were controlled for using logistic and linear regressions.

MAIN OUTCOME MEASURES

Mental disorders (composite international diagnostic interview, CIDI), depressivity (Beck Depression Inventory, BDI), psychological distress (general health questionnaire, GHQ-12), perceived health, and subjective quality of life.

RESULTS

Approximately 20% of women and 9% of men reported having experienced infertility. Childless women with infertility experience had increased adjusted risks for dysthymia (OR 3.41, 95% CI; 1.01-11.5) and anxiety disorders (2.67, 1.00-7.12) compared to women who had not experienced infertility. Women with infertility experience but with a current child had an increased risk for panic disorder (2.58, 1.11-6.01). Childless men with infertility experience had a significantly poorer quality of life compared to men without infertility.

CONCLUSIONS

Infertility was associated with mental health, especially dysthymia and anxiety. The results differed by gender and the permanency of infertility. Gender-specific psychosocial support and follow-up for infertile people is warranted.

摘要

目的

早期研究表明,不孕不育和心理健康问题是相关的,不孕不育对女性和男性的体验是不同的。本基于人群的研究旨在调查经历过不孕不育的女性和男性的精神障碍、抑郁、心理困扰、健康感知和生活质量。

设计

全国性的横断面健康 2000 调查。

设置

基于人群。

人群

年龄在 30-44 岁的芬兰代表性随机样本(n = 2291)。

方法

将经历过不孕不育的人(n = 338)与其余人群的结果进行比较。使用逻辑回归和线性回归控制年龄、婚姻状况、教育程度、收入、体重指数和吸烟情况。

主要观察指标

精神障碍(复合国际诊断访谈,CIDI)、抑郁(贝克抑郁量表,BDI)、心理困扰(一般健康问卷,GHQ-12)、健康感知和主观生活质量。

结果

大约 20%的女性和 9%的男性报告经历过不孕不育。与未经历过不孕不育的女性相比,不孕不育且无子女的女性发生心境恶劣(OR 3.41,95%CI;1.01-11.5)和焦虑障碍(2.67,1.00-7.12)的调整后风险增加。有不孕不育经历但有现有孩子的女性发生惊恐障碍的风险增加(2.58,1.11-6.01)。无子女且不孕不育的男性生活质量明显较差。

结论

不孕不育与心理健康有关,尤其是心境恶劣和焦虑。结果因性别和不孕不育的永久性而异。需要为不孕不育人群提供性别特异性的心理社会支持和随访。

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