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[从旅行者腹泻中分离出的侵袭性大肠杆菌O121:H-]

[Enteroinvasive Escherichia coli O121: H- isolated from travellers' diarrhea].

作者信息

Hiruta N, Himori M, Habutsu M, Okamura N, Ogawa M, Matsushita S, Kudoh Y

机构信息

Yokosuka City Institute of Public Health.

出版信息

Kansenshogaku Zasshi. 1991 May;65(5):537-9. doi: 10.11150/kansenshogakuzasshi1970.65.537.

Abstract

A lactose slow-fermenting, non motile Escherichia coli strain was isolated from a diarrheal patient returning from Indonesia. Examination of virulence of the strain showed that it penetrated into tissue culture cells, and were positive in Serény test and enzyme-linked immunosorbent assay for detection of enteroinvasive E. coli. A large plasmid responsible for virulence was also detected. Thus the strain was confirmed to be a typical enteroinvasive E. coli. Analysis of O serotype using the antisera against E. coli O1-O170 revealed that the strain had O121 antigen, whose antiserum is not included in the commercial serotyping kit for the diagnosis of diarrheagenic E. coli.

摘要

从一名从印度尼西亚回国的腹泻患者身上分离出一株乳糖发酵缓慢、无运动性的大肠杆菌菌株。对该菌株的毒力检测表明,它能侵入组织培养细胞,在用于检测肠侵袭性大肠杆菌的塞雷尼试验和酶联免疫吸附试验中呈阳性。还检测到一个与毒力相关的大质粒。因此,该菌株被确认为典型的肠侵袭性大肠杆菌。使用针对大肠杆菌O1 - O170的抗血清进行O血清型分析,结果显示该菌株具有O121抗原,其抗血清不包含在用于诊断致泻性大肠杆菌的商业血清分型试剂盒中。

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