异鼠李素在玻碳电极上的电化学行为研究及其应用
Study of the electrochemical behavior of isorhamnetin on a glassy carbon electrode and its application.
作者信息
Liu Ai-Lin, Zhang Shao-Bo, Chen Wei, Huang Li-Ying, Lin Xin-Hua, Xia Xing-Hua
机构信息
Department of Pharmaceutical Analysis, Faculty of Pharmacy, Fujian Medical University, Fuzhou 350004, PR China.
出版信息
Talanta. 2008 Oct 19;77(1):314-8. doi: 10.1016/j.talanta.2008.06.030. Epub 2008 Jul 1.
The electrochemical behavior of isorhamnetin (ISO) at a glassy carbon electrode was studied in a phosphate buffer solution (PBS) of pH 4.0 by cyclic voltammetry (CV) and differential pulse voltammetric method (DPV). A well-defined redox wave of ISO involving one electrons and one proton appeared. The electrode reaction is a reactant weak adsorption-controlled process with a charge transfer coefficient (alpha) of 0.586. Based on the understanding of the electrochemical process of ISO at the glassy carbon electrode, analysis of ISO can be realized. Under optimal conditions, the oxidation peak current showed linear dependence on the concentration of ISO in the range of 1.0x10(-8) to 4.0x10(-7)M and 1.0x10(-6) to 1.0x10(-5)M. The detection limit is 5.0x10(-9)M. This method has been successfully applied to the detection of ISO in tablets.
采用循环伏安法（CV）和差分脉冲伏安法（DPV），在pH 4.0的磷酸盐缓冲溶液（PBS）中研究了异鼠李素（ISO）在玻碳电极上的电化学行为。出现了一个明确的涉及一个电子和一个质子的ISO氧化还原波。电极反应是一个反应物弱吸附控制的过程，电荷转移系数（α）为0.586。基于对ISO在玻碳电极上电化学过程的理解，可以实现对ISO的分析。在最佳条件下，氧化峰电流在1.0×10⁻⁸至4.0×10⁻⁷M以及1.0×10⁻⁶至1.0×10⁻⁵M范围内与ISO浓度呈线性关系。检测限为5.0×10⁻⁹M。该方法已成功应用于片剂中ISO的检测。
Zotero 插件