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脂质组学的技术发展

Technological developments in lipidomics.

作者信息

Hou Weimin, Zhou Hu, Elisma Fred, Bennett Steffany A L, Figeys Daniel

机构信息

Chemistry department, University of Ottawa, Ottawa, Ontario, Canada K1H 8M5.

出版信息

Brief Funct Genomic Proteomic. 2008 Sep;7(5):395-409. doi: 10.1093/bfgp/eln042. Epub 2008 Sep 19.

Abstract

Lipid analysis is a well-established field of research that focuses on one lipid or a few lipids. The recent developments in mass spectrometry technologies have enabled more comprehensive studies to be performed on lipids present in a sample. The move towards extensive lipid research has led to the coining of the term lipidomics, which is defined as the ensemble of lipids present in a sample. In this review, we will discuss the technical developments in the field of lipidomics and the current limitations of this nascent field.

摘要

脂质分析是一个成熟的研究领域,专注于一种或几种脂质。质谱技术的最新发展使得能够对样品中存在的脂质进行更全面的研究。向广泛脂质研究的转变催生了“脂质组学”这一术语,它被定义为样品中存在的脂质的集合。在本综述中,我们将讨论脂质组学领域的技术发展以及这个新兴领域目前的局限性。

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