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基于质谱的脂质组学在乳制品领域的研究进展

Progress of Mass Spectrometry-Based Lipidomics in the Dairy Field.

作者信息

Ren Wei, Sun Mengqi, Shi Xiaoyuan, Wang Tianqi, Wang Yonghui, Wang Changfa, Li Mengmeng

机构信息

School of Agricultural Science and Engineering, Liaocheng Research Institute of Donkey High-Efficiency Breeding and Ecological Feeding, Liaocheng University, Liaocheng 252000, China.

出版信息

Foods. 2023 May 23;12(11):2098. doi: 10.3390/foods12112098.

DOI:10.3390/foods12112098
PMID:37297344
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10252832/
Abstract

Lipids play important biological roles, such as providing essential fatty acids and signaling. The wide variety and structural diversity of lipids, and the limited technical means to study them, have seriously hampered the resolution of the mechanisms of action of lipids. With advances in mass spectrometry (MS) and bioinformatic technologies, large amounts of lipids have been detected and analyzed quickly using MS-based lipidomic techniques. Milk lipids, as complex structural metabolites, play a crucial role in human health. In this review, the lipidomic techniques and their applications to dairy products, including compositional analysis, quality identification, authenticity identification, and origin identification, are discussed, with the aim of providing technical support for the development of dairy products.

摘要

脂质发挥着重要的生物学作用,如提供必需脂肪酸和信号传导。脂质种类繁多、结构多样,且研究它们的技术手段有限,这严重阻碍了脂质作用机制的解析。随着质谱(MS)和生物信息学技术的进步,基于MS的脂质组学技术已能快速检测和分析大量脂质。乳脂作为复杂的结构代谢产物,对人类健康起着至关重要的作用。本文综述了脂质组学技术及其在乳制品中的应用,包括成分分析、质量鉴定、真伪鉴定和产地鉴定,旨在为乳制品的发展提供技术支持。

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本文引用的文献

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A Comprehensive Review of Lipidomics and Its Application to Assess Food Obtained from Farm Animals.脂质组学及其在评估农场动物源性食品中的应用综述
Food Sci Anim Resour. 2022 Jan;42(1):1-17. doi: 10.5851/kosfa.2021.e59. Epub 2022 Jan 1.
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Comparative Analysis of Triglycerides From Different Regions and Mature Lactation Periods in Chinese Human Milk Project (CHMP) Study.中国母乳项目(CHMP)研究中不同地区及成熟哺乳期母乳甘油三酯的比较分析
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基于非靶向脂质组学的牦牛、水牛和奶牛初乳中脂质的组成及结构特征
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Identification and Quantification of Triacylglycerols Using Ultraperformance Supercritical Fluid Chromatography and Quadrupole Time-of-Flight Mass Spectrometry: Comparison of Human Milk, Infant Formula, Other Mammalian Milk, and Plant Oil.采用超高效超临界流体色谱和四极杆飞行时间质谱法鉴定和定量三酰基甘油:人乳、婴儿配方奶粉、其他哺乳动物奶和植物油的比较。
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