Brazier John
School of Health and Related Research, University of Sheffield, Sheffield, UK.
J Health Serv Res Policy. 2008 Oct;13 Suppl 3:70-5. doi: 10.1258/jhsrp.2008.008015.
This article presents research undertaken as part of a wider programme of work concerned with measuring and health and wellbeing for economic evaluation. The focus is on developing quality adjusted life years (QALYs) in mental health, but the issues are common across all areas of health care. The article begins by reviewing the issues of what should be valued (health or broader notions of wellbeing), how mental health and wellbeing should be described, how mental health states should be valued and who should do the valuing. The article presents four pieces of work. The first is a re-analysis of the ONS Psychiatric Morbidity 2000 Survey to provide evidence on the relevance of generic measures across different mental health disorders. It found that common mental health problems, such as anxiety and depression, had a significant impact on the generic preference-based measure of health in the SF-6D, but psychosis and personality disorders did not. The article then presents two studies using the ratings of people experiencing the states of health. Both studies found that people experiencing different health states gave mental health greater weight than physical health compared to members of the general public trying to imagine the health states. Finally, the article presents a study developing a condition-specific preference-based measure for calculating QALYs from an existing measure of mental health, the CORE-OM, using modern psychometric methods to construct health states amenable to valuation. It also considers a proposal to develop an entirely new QALY measure in mental health.
本文介绍了一项研究,该研究是一个更广泛的工作项目的一部分,该项目涉及为经济评估衡量健康与幸福。重点是在精神卫生领域制定质量调整生命年(QALYs),但这些问题在所有医疗保健领域都很常见。本文首先回顾了以下问题:应该重视什么(健康还是更广泛的幸福概念)、应如何描述精神健康与幸福、应如何评估精神健康状态以及应由谁来进行评估。本文介绍了四项工作。第一项是对英国国家统计局2000年精神病发病率调查进行重新分析,以提供关于通用测量方法在不同精神障碍中的相关性的证据。研究发现,常见的精神健康问题,如焦虑和抑郁,对SF - 6D中基于偏好的通用健康测量方法有重大影响,但精神病和人格障碍则没有。然后本文介绍了两项利用健康状况体验者评分的研究。两项研究均发现,与试图想象健康状况的普通公众相比,体验不同健康状况的人给予精神健康的权重高于身体健康。最后,本文介绍了一项研究,该研究利用现代心理测量方法构建适合评估的健康状态,从现有的精神健康测量方法CORE - OM开发一种针对特定疾病的基于偏好的测量方法来计算QALYs。它还考虑了一项在精神卫生领域开发全新QALY测量方法的提议。