Nève de Mévergnies Constance, Verhaeghe Nick, Koster Ernst H W, Baeken Chris, Vander Zwalmen Yannick, Hoorelbeke Kristof
Department of Experimental Clinical and Health Psychology, Ghent University, Ghent, Belgium.
Department of Public Health and Primary Care, Ghent University, Ghent, Belgium.
JMIR Ment Health. 2023 Aug 18;10:e44679. doi: 10.2196/44679.
Depression is a serious and burdensome psychiatric illness that contributes heavily to health expenditures. These costs are partly related to the observation that depression is often not limited to a single episode but can recur or follow a chronic pathway. In terms of risk factors, it is acknowledged that cognitive impairments play a crucial role in vulnerability to depression. Within this context, cognitive control training (CCT) has shown its effectiveness in reducing the risk for recurrence of depression. CCT is low cost intensive and can be provided as a web-based intervention, which makes it easy to disseminate. Despite increasing interest in the field, studies examining the cost-effectiveness of CCT in the context of depression are largely missing. Health economic evaluation (HEE) allows to inform decision makers with evidence-based insights about how to spend limited available (financial) resources in the most efficient way. HEE studies constitute a crucial step in the implementation of a new intervention in clinical practice. Approaching preventive measures for depression such as CCT from an HEE perspective is informative to health policy, fostering optimal use of health expenditures. The aim of this paper was to inform and guide researchers during the phase of designing HEE studies in the context of CCT for depression. A clear view of CCT's cost-effectiveness is paramount for its clinical implementation.
抑郁症是一种严重且负担沉重的精神疾病，对医疗支出有很大影响。这些成本部分与以下观察结果有关：抑郁症往往不限于单次发作，而是可能复发或呈慢性病程。就风险因素而言，人们公认认知障碍在抑郁症易感性中起着关键作用。在此背景下，认知控制训练（CCT）已显示出其在降低抑郁症复发风险方面的有效性。CCT成本低且强度大，可以作为基于网络的干预措施提供，这使其易于传播。尽管该领域的关注度不断提高，但在抑郁症背景下研究CCT成本效益的研究却基本缺失。卫生经济评估（HEE）能够为决策者提供基于证据的见解，以便他们以最有效的方式使用有限的（财政）资源。HEE研究是在临床实践中实施新干预措施的关键一步。从HEE角度探讨抑郁症的预防措施，如CCT，对卫生政策具有指导意义，有助于优化医疗支出的使用。本文的目的是在为抑郁症设计基于CCT的HEE研究阶段为研究人员提供信息并给予指导。清楚了解CCT的成本效益对于其临床应用至关重要。
