Hube B, Turver C J, Odds F C, Eiffert H, Boulnois G J, Köchel H, Rüchel R
Hygiene-Institut der Universität, Göttingen, Germany.
J Med Vet Mycol. 1991;29(2):129-32.
The gene encoding the Candida albicans aspartate proteinase that is secreted by cells grown in protein-containing media was cloned from a C. albicans genomic bank. The base sequence of the insert shows a 1173 bp open-reading frame and indicates an amino acid sequence typical of aspartate proteinases, with amino acid sequence homology to other enzymes of this class and a putative signal peptide consisting of 50 amino acids upstream of the active enzyme.
从白色念珠菌基因组文库中克隆了编码在含蛋白质培养基中生长的细胞所分泌的白色念珠菌天冬氨酸蛋白酶的基因。插入片段的碱基序列显示有一个1173bp的开放阅读框，表明其氨基酸序列是天冬氨酸蛋白酶的典型序列，与该类别的其他酶具有氨基酸序列同源性，并且在活性酶上游有一个由50个氨基酸组成的推定信号肽。
