Iwata Tomonori, Mori Takahisa, Tajiri Hiroyuki
Department of Stroke Treatment, Shonan Kamakura General Hospital, 1202-1 Yamazaki, Kamakura, Kanagawa 247-8533, Japan.
Brain Nerve. 2008 Sep;60(9):1067-72.
An 84-year-old woman who had experienced a sudden onset of stupor and total aphasia and right-side hemiparesis was admitted to our institution. Emergency MR (diffusion-weighted images: DWIs) studies revealed ischemic changes in the territory of the left middle cerebral artery; findings from the perfusion-weighted images (PWIs) has suggested a reduction of the cerebral blood flow. In addition, the MR angiograms showed no signals in the left carotid-middle cerebral artery. An emergency removal of the clot the carotid artery was attempted after an adaptive determination of revascularization was performed using MRI (DWIs/PWIs) during the acute stage. An emergency cerebral angiography demonstrated occlusion of the left internal carotid artery (ICA). In order to prevent the migration of thrombus into the peripheral arteries, the proximal blood flow was blocked using a 9-F guiding catheter with a coaxial balloon. Manual aspiration through the catheter with a 10-ml syringe resulted in effective removal of the thrombus. The thrombus was thus removed successfully, and the cerebral angiography after clot removal therapy (CRT) demonstrated complete recanalization of the left ICA. The patient's National Institutes of Health Stroke score decreased from 25 to 1 at 8 days after clot removal and a good 3-month clinical outcome was achieved. CRT by simple aspiration may be considered as a feasible and effective treatment modality for patients with embolic carotid occlusion. Received: December 18, 2007, Accepted: June 4, 2008
一名84岁女性因突发昏迷、完全失语和右侧偏瘫入住我院。紧急磁共振成像(扩散加权成像:DWI)研究显示左侧大脑中动脉供血区域存在缺血性改变;灌注加权成像(PWI)结果提示脑血流量减少。此外,磁共振血管造影显示左侧颈内动脉-大脑中动脉无信号。在急性期使用MRI(DWI/PWI)进行血管再通适应性判定后,尝试紧急清除颈动脉内的血栓。紧急脑血管造影显示左侧颈内动脉(ICA)闭塞。为防止血栓迁移至外周动脉,使用带有同轴球囊的9F引导导管阻断近端血流。用10ml注射器通过导管手动抽吸有效清除了血栓。血栓因此被成功清除,血栓清除治疗(CRT)后的脑血管造影显示左侧ICA完全再通。患者的美国国立卫生研究院卒中量表评分在血栓清除后8天从25降至1,并在3个月时取得了良好的临床结果。对于栓塞性颈动脉闭塞患者,单纯抽吸的CRT可被视为一种可行且有效的治疗方式。收稿日期:2007年12月18日,接受日期:2008年6月4日