Shimizu M, Sugihara N, Kita Y, Shimizu K, Shibayama S, Takeda R
Second Department of Internal Medicine, School of Medicine, Kanazawa University, Japan.
Jpn Circ J. 1991 Jul;55(7):657-64. doi: 10.1253/jcj.55.657.
Indices of left ventricular ejection and diastolic filling were measured by cineventriculography in 11 patients with non-insulin dependent diabetes mellitus without significant coronary stenosis and 11 control subjects without diabetes mellitus. Indices of left ventricular ejection, such as ejection fraction and peak ejection rate, were the same in the two groups. The left ventricular end-diastolic volume index and the rapid filling volume index were significantly smaller, the peak filling rate was lower, the left ventricular end-diastolic pressure was higher and the modulus of left ventricular chamber stiffness was larger in the diabetic patients than in the control subjects. These results indicate that left ventricular chamber stiffness is increased in patients with non-insulin dependent diabetes mellitus.
通过心血管造影术测量了11例无明显冠状动脉狭窄的非胰岛素依赖型糖尿病患者及11例无糖尿病的对照者的左心室射血和舒张期充盈指标。两组的左心室射血指标，如射血分数和峰值射血率相同。糖尿病患者的左心室舒张末期容积指数和快速充盈容积指数显著更小，峰值充盈率更低，左心室舒张末期压力更高，左心室腔僵硬度模量更大。这些结果表明，非胰岛素依赖型糖尿病患者的左心室腔僵硬度增加。
