Nishimura Y, Nakamitsu M, Hattori T, Takatsuki K, Ito H, Fukutake K, Fujimaki M
Blood Transfusion Service, Kumamoto University Hospital.
Rinsho Byori. 1991 Jun;39(6):623-6.
We evaluated Retrovirus EIA kit (Roche Co.), in which virus components of three different viruses, HIV-1, HIV-2, and HTLV-I were used antigens. All the specimens from the patients with ATL, HAM, HTLV-I carrier, AIDS and AC, and from HIV-2 infected individuals were found to be positive. Four out of 40 specimens from hemophiliacs not infected with HIV-1 were found out to be positive. These specimens were confirmed to contain antibody against HTLV-I. Pseudo-negative or -positive reactions were not found in this study. Therefore, Retrovirus EIA kit should be evaluated more extensively, for the possible applications for screening of blood donors, and for selecting the sources of blood products as well as for clinical diagnoses.
我们评估了逆转录病毒酶免疫分析试剂盒（罗氏公司），该试剂盒使用三种不同病毒（HIV-1、HIV-2和HTLV-I）的病毒成分作为抗原。所有来自成人T细胞白血病（ATL）、热带痉挛性截瘫（HAM）、HTLV-I携带者、艾滋病（AIDS）和艾滋病相关综合征（AC）患者以及HIV-2感染个体的标本均呈阳性。在40例未感染HIV-1的血友病患者的标本中，有4例呈阳性。这些标本被证实含有抗HTLV-I抗体。本研究未发现假阴性或假阳性反应。因此，逆转录病毒酶免疫分析试剂盒应进行更广泛的评估，以用于筛选献血者、选择血液制品来源以及临床诊断等可能的应用。
