Nomoto Koji
Yakult Central Institute for Microbiological Research, 1796 Yaho, Kunitachishi, Tokyo 186-8650, Japan.
Indian J Exp Biol. 2008 Aug;46(8):557-61.
Prevention of infectious complications after major surgeries including those for cancer has been a major concern in the clinical field. To overcome this problem, probiotics and synbiotics (combination of probiotics and prebiotics have recently been introduced for post-operative treatment. Clinical application of synbiotics in severe cases, such as severe pediatric surgical cases, acute pancreatitis, liver transplantation, and biliary cancer, has been reported. The present article deals with the clinical effect of such synbiotic therapies for the patients under emergency medical care, and discusses the possible mechanism of action and prospect of synbiotic therapy.
预防包括癌症手术在内的大手术后的感染并发症一直是临床领域的主要关注点。为克服这一问题,益生菌和合生元(益生菌与益生元的组合)最近已被引入术后治疗。已有报道称合生元在严重病例中的临床应用,如重症儿科手术病例、急性胰腺炎、肝移植和胆管癌。本文探讨了这种合生元疗法对急诊患者的临床效果,并讨论了合生元疗法可能的作用机制和前景。