Trepnau Daniela, Ulrich Evelyn, Uhlig Reinhard, Lindner Thomas, Selbitz Hans-Joachim, Rösler Uwe, Gabert Jörg, Bergfeld Uwe, Fehlhaber Karsten, Brabetz Werner, Lehmann Jörg
Labor Diagnostik GmbH Leipzig, Leipzig.
Berl Munch Tierarztl Wochenschr. 2008 Sep-Oct;121(9-10):334-40.
In Germany now, the recognition of Salmonella infections in pig herds is based on three different commercial tests detecting antibodies against Salmonella-derived lipopolysaccharide (LPS). However, a serious disadvantage of these tests, used so far, is the restricted detection of antibodies belonging predominantly to the immunoglobulin class g (IgG). Therefore, a new test was developed to detect three Ig classes (IgM, IgG and IgA). Different constellations between the three Ig classes allow the evaluation of the current infection status of each pig. Under field conditions, this was proved in three different vaccination trials using a commercial Salmonella Typhimurium live vaccine.
目前在德国，猪群中沙门氏菌感染的识别基于三种不同的商业检测方法，这些方法用于检测针对沙门氏菌衍生脂多糖（LPS）的抗体。然而，迄今为止使用的这些检测方法的一个严重缺点是，主要检测的是属于免疫球蛋白g类（IgG）的抗体，检测范围有限。因此，开发了一种新的检测方法来检测三种免疫球蛋白类别（IgM、IgG和IgA）。三种免疫球蛋白类别之间的不同组合可以评估每头猪当前的感染状况。在田间条件下，通过三项使用市售鼠伤寒沙门氏菌活疫苗的不同疫苗接种试验证明了这一点。
