Belkin Z P, Levenson V I, Egorova T P
Zh Mikrobiol Epidemiol Immunobiol. 1991 Apr(4):47-50.
Ribosomal preparations from Shigella flexneri and Shigella sonnei, introduced parenterally into mice, enhance their resistance to infection with the causative agents of typhoid fever and staphylococci. This effect is considerably less pronounced than that produced by the preparation of homologous lipopolysaccharide isolated by Boivin's method. After the administration of ribosomes nonspecific resistance to bacterial infective agents lasts for a short time. Ribosomal preparations do not enhance the resistance of mice to the lethal action of endotoxin.
将弗氏志贺菌和宋内志贺菌的核糖体制剂经肠胃外途径注入小鼠体内后，可增强其对伤寒热病原体和葡萄球菌感染的抵抗力。这种效果远不如用博伊文氏法分离出的同源脂多糖制剂所产生的效果显著。注射核糖体后，对细菌病原体的非特异性抵抗力持续时间较短。核糖体制剂不会增强小鼠对内毒素致死作用的抵抗力。
