Okiyama N, Kohsaka H, Ueda N, Satoh T, Katayama I, Nishioka K, Yokozeki H
Department of Dermatology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.
Dermatology. 2008;217(4):374-7. doi: 10.1159/000158637. Epub 2008 Oct 1.
Although dermatomyositis (DM)-associated facial erythema was noted in the nasolabial folds of Japanese patients, DM-associated facial erythema other than heliotrope rash has drawn little attention in previous studies.
To characterize phenotypical features and frequencies of erythema, especially those in the seborrheic area of the head, in DM patients.
A retrospective study on skin manifestations in 33 DM patients followed up at our department during the past 15 years was conducted.
Macular violaceous erythema (MVE) in the seborrheic area of the face was most frequent (67%). Patients with facial MVE had also MVE in the scalp significantly more frequently than those without facial MVE. The pathology of the facial MVE was dominated by DM-associated changes with slight changes compatible with seborrheic dermatitis (SD).
Japanese DM patients had MVE frequently in the seborrheic area of the head. Its phenotypical features suggested that it might be triggered by SD.
尽管在日本皮肌炎（DM）患者的鼻唇沟处发现了与DM相关的面部红斑，但除了向阳疹之外，以往研究中对与DM相关的其他面部红斑关注较少。
描述DM患者红斑的表型特征和发生率，尤其是头部脂溢性区域的红斑。
对过去15年在我科随访的33例DM患者的皮肤表现进行回顾性研究。
面部脂溢性区域的斑状紫红斑（MVE）最为常见（67%）。面部有MVE的患者头皮出现MVE的频率也显著高于无面部MVE的患者。面部MVE的病理以DM相关改变为主，伴有与脂溢性皮炎（SD）相符的轻微改变。
日本DM患者头部脂溢性区域经常出现MVE。其表型特征提示可能由SD引发。
