• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

埃什特雷拉山地犬的被动髋关节松弛——牵引指数、遗传力和育种值

Passive hip laxity in Estrela Mountain Dog--distraction index, heritability and breeding values.

作者信息

Ginja Mário M D, Silvestre António M, Ferreira António J A, Gonzalo-Orden José M, Orden Maria A, Melo-Pinto Pedro, Llorens-Pena Maria P, Colaço Jorge

机构信息

Department of Veterinary Sciences-CITAB, University of Trás-os-Montes e Alto Douro, Portugal.

出版信息

Acta Vet Hung. 2008 Sep;56(3):303-12. doi: 10.1556/AVet.56.2008.3.4.

DOI:10.1556/AVet.56.2008.3.4
PMID:18828482
Abstract

Two hundred and fifteen Estrela Mountain Dogs (EMD) were examined using the PennHIP method between 2002 and 2006. Passive hip laxity (PHL) was estimated calculating the distraction index (DI). Pedigree information was obtained from the Portuguese Kennel Club. The heritability and breeding values were estimated using the linear Animal Model. The DI, using as reference the worst joint of each animal, ranged from 0.15 to 1.12 (0.55 +/- 0.19). The PHL was equal in right and left sides, and was higher in females than in males (P > 0.05 and P <0.01 in the t-test, respectively). The estimated heritability was 0.83 +/- 0.11. The mean breeding values for PHL were stable in EMD born between 1991 and 2003, and showed an improvement in 2004 and 2005. The data confirm high PHL in breeds with high prevalence and severity of canine hip dysplasia. The high heritability indicates that the DI could be reduced in the breed if PHL were used as a selection criterion. The early favourable evolution of DI breeding values could be related with the increase of voluntary radiographic hip screening in the last years, and the subsequent introduction of hip quality as a breeding criterion.

摘要

2002年至2006年间,采用宾夕法尼亚大学髋关节评估方法(PennHIP)对215只埃斯特雷拉山地犬(EMD)进行了检查。通过计算牵引指数(DI)来估计被动性髋关节松弛度(PHL)。系谱信息来自葡萄牙养犬俱乐部。使用线性动物模型估计遗传力和育种值。以每只动物最差的关节为参照,DI范围为0.15至1.12(0.55±0.19)。PHL在左右两侧相等,且雌性高于雄性(t检验中P值分别>0.05和<0.01)。估计的遗传力为0.83±0.11。1991年至2003年间出生的EMD中,PHL的平均育种值较为稳定,在2004年和2005年有所改善。数据证实,在犬髋关节发育不良患病率和严重程度较高的品种中,PHL较高。高遗传力表明,如果将PHL用作选择标准,该品种的DI可能会降低。DI育种值的早期良好演变可能与过去几年自愿进行的髋关节X线筛查增加以及随后将髋关节质量作为育种标准的引入有关。

相似文献

1
Passive hip laxity in Estrela Mountain Dog--distraction index, heritability and breeding values.埃什特雷拉山地犬的被动髋关节松弛——牵引指数、遗传力和育种值
Acta Vet Hung. 2008 Sep;56(3):303-12. doi: 10.1556/AVet.56.2008.3.4.
2
Provisional heritability estimates of four distraction index traits in a breeding population of German Shepherd dogs.德国牧羊犬繁殖群体中四个注意力分散指数性状的临时遗传力估计值。
N Z Vet J. 2018 Nov;66(6):319-324. doi: 10.1080/00480169.2018.1512429. Epub 2018 Sep 2.
3
Hip dysplasia in Estrela mountain dogs: prevalence and genetic trends 1991-2005.埃斯特雷拉山地犬髋关节发育不良:1991 - 2005年的患病率及遗传趋势
Vet J. 2009 Nov;182(2):275-82. doi: 10.1016/j.tvjl.2008.06.014. Epub 2008 Aug 21.
4
Comparison of estimates of hip dysplasia genetic parameters in Estrela Mountain Dog using linear and threshold models.使用线性模型和阈值模型对埃什特雷拉山地犬髋关节发育不良遗传参数估计值的比较。
J Anim Sci. 2007 Aug;85(8):1880-4. doi: 10.2527/jas.2007-0166. Epub 2007 Apr 27.
5
Distraction index as a risk factor for osteoarthritis associated with hip dysplasia in four large dog breeds.作为四个大型犬种髋关节发育不良相关骨关节炎风险因素的牵引指数
J Small Anim Pract. 2010 May;51(5):264-9. doi: 10.1111/j.1748-5827.2010.00937.x.
6
Advances in diagnosing canine hip dysplasia.犬髋关节发育不良诊断的进展
J Am Vet Med Assoc. 1997 May 15;210(10):1451-7.
7
Early hip laxity examination in predicting moderate and severe hip dysplasia in Estrela mountain dog.早期髋关节松弛检查对预测埃斯特雷拉山地犬中度和重度髋关节发育不良的作用
J Small Anim Pract. 2008 Dec;49(12):641-6. doi: 10.1111/j.1748-5827.2008.00629.x. Epub 2008 Aug 5.
8
Genetic improvement of hip-extended scores in 3 breeds of guide dogs using estimated breeding values: Notable progress but more improvement is needed.利用估计育种值提高 3 个导盲犬品种髋关节伸展评分:取得显著进展,但仍需进一步改进。
PLoS One. 2019 Feb 22;14(2):e0212544. doi: 10.1371/journal.pone.0212544. eCollection 2019.
9
Genetic evaluation of the total hip score of four populous breeds of dog, as recorded by the New Zealand Veterinary Association Hip Dysplasia Scheme (1991-2011).新西兰兽医协会髋关节发育不良计划(1991 - 2011年)记录的四个犬类常见品种全髋关节评分的遗传评估。
N Z Vet J. 2015 Mar;63(2):79-85. doi: 10.1080/00480169.2014.961581. Epub 2015 Jan 27.
10
Reliability of the hip distraction index in two-month-old German shepherd dogs.两个月大德国牧羊犬髋关节牵张指数的可靠性
J Am Vet Med Assoc. 1998 May 15;212(10):1560-3.

引用本文的文献

1
Genomic prediction and genome-wide association studies of morphological traits and distraction index in Korean Sapsaree dogs.韩国萨普莱斯犬形态特征和分离指数的基因组预测和全基因组关联研究。
PLoS One. 2024 Nov 21;19(11):e0312583. doi: 10.1371/journal.pone.0312583. eCollection 2024.
2
The utilization of the Vezzoni modified Badertscher distension device in breeding programs: Heritability estimates and effect on the hip dysplasia prevalence.在繁育计划中使用 Vezzoni 改良 Badertscher 扩张器:遗传力估计值及其对髋关节发育不良流行率的影响。
PLoS One. 2024 Aug 20;19(8):e0308984. doi: 10.1371/journal.pone.0308984. eCollection 2024.
3
Early hip laxity screening and later canine hip dysplasia development.
早期髋关节松弛筛查与后期犬髋关节发育不良的发展
Vet World. 2022 Mar;15(3):679-684. doi: 10.14202/vetworld.2022.679-684. Epub 2022 Mar 24.
4
Emerging insights into the genetic basis of canine hip dysplasia.对犬髋关节发育不良遗传基础的新见解。
Vet Med (Auckl). 2015 May 20;6:193-202. doi: 10.2147/VMRR.S63536. eCollection 2015.
5
A retrospective study on findings of canine hip dysplasia screening in Kenya.肯尼亚犬髋关节发育不良筛查结果的回顾性研究。
Vet World. 2015 Nov;8(11):1326-30. doi: 10.14202/vetworld.2015.1326-1330. Epub 2015 Nov 22.
6
Estimated breeding values for canine hip dysplasia radiographic traits in a cohort of Australian German Shepherd dogs.澳大利亚德国牧羊犬髋关节发育不良放射学特征的估计育种值。
PLoS One. 2013 Oct 29;8(10):e77470. doi: 10.1371/journal.pone.0077470. eCollection 2013.