Li Yong-Yong, Dai Yu, Zhang Xian-Zheng, Zhuo Ren-Xi
Key Laboratory of Biomedical Polymers of Ministry of Education & Department of Chemistry, Wuhan University, Wuhan, PR China.
J Colloid Interface Sci. 2008 Dec 1;328(1):211-5. doi: 10.1016/j.jcis.2008.09.008. Epub 2008 Sep 6.
Poly(N-isopropylacrylamide)-b-poly(vinylpyridine) (PNIPAAm-b-PVP) and poly(N-isopropylacrylamide-co-hydroxylethyl methacrylate)-b-poly(vinylphenol) (P(NIPAAm-co-HEMA)-b-PVPhol) were synthesized by reversible addition-fragmentation chain transfer (RAFT) polymerization. Above two copolymers could form complex in pure water and in DMF/water environment with the DMF content lower than 40% by hydrogen bondings. The morphologies of the complex were investigated by transmission electron microscope (TEM). It was found that the dimension of the complex in strong acid (pH 1.0) or base environment (pH 12.0) was smaller than the one in weak acid or in neutral environment. After the shell cross-linking of the complex, the complex showed a type of "swollen" state in acid or base environment which is similar to the properties of microgel.
通过可逆加成-断裂链转移（RAFT）聚合反应合成了聚（N-异丙基丙烯酰胺）-b-聚（乙烯基吡啶）（PNIPAAm-b-PVP）和聚（N-异丙基丙烯酰胺-共-甲基丙烯酸羟乙酯）-b-聚（乙烯基苯酚）（P（NIPAAm-共-HEMA）-b-PVPhol）。上述两种共聚物在纯水中以及在DMF含量低于40%的DMF/水环境中可通过氢键形成复合物。通过透射电子显微镜（TEM）研究了该复合物的形态。发现在强酸（pH 1.0）或碱性环境（pH 12.0）中复合物的尺寸小于在弱酸或中性环境中的尺寸。复合物进行壳交联后，在酸或碱环境中呈现出一种类似于微凝胶性质的“溶胀”状态。
