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Assembly system of direct modified superparamagnetic iron oxide nanoparticles for target-specific MRI contrast agents.

作者信息

Tanaka Kazuo, Kitamura Narufumi, Morita Masahito, Inubushi Toshiro, Chujo Yoshiki

机构信息

Department of Polymer Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510, Japan.

出版信息

Bioorg Med Chem Lett. 2008 Oct 15;18(20):5463-5. doi: 10.1016/j.bmcl.2008.09.035. Epub 2008 Sep 11.

DOI:10.1016/j.bmcl.2008.09.035
PMID:18829309
Abstract

We report the direct modification of SPIOs with a biomolecule and the target-specific assembly system of these modified SPIOs for using MRI contrast agents. The transverse relaxation rate of the aqueous solutions containing the modified SPIOs was altered by the dispersion state.

摘要

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