Bai Bing, Li Ming-Jing, Wang Yong, Liu Xiu-Hua
Henan University, Key Lab of Natural Drug and Immune Engineering of Henan Province, College of Chemistry and Chemical Engineering, Kaifeng 475001, China.
Zhongguo Zhong Yao Za Zhi. 2008 Jun;33(11):1272-4.
To study the chemical constituents of Dioscorea opposita.
The chemical constituents were isolated and purified by silica gel column chromatography, and the structures were elucidated by their spectroscopic data and physico-chemical properties.
Twelve compounds were obtained and identified as palmitic acid (1), beta-sitosterol (2), oleic acid (3), beta-sitosterol acetate (4), 5-(hydroxymethyl)furfural (5), nonanedioic acid (6), beta-daucosterol (7), cyclo-(Phe-Tyr) (8), cyclo-(Tyr-Tyr) (9), 6-methyl citrate (10), 1, 5-dimethyl citrate (11), trimethyl citrate (12).
Compounds 3-12 were isolated from this plant for the first time and cyclodipeptides were firstly isolated from the Dioscoreae family; Compound 9 was a new natural product.
研究山药的化学成分。
采用硅胶柱色谱法对化学成分进行分离纯化，并通过光谱数据和理化性质对其结构进行鉴定。
得到12个化合物，分别鉴定为棕榈酸（1）、β-谷甾醇（2）、油酸（3）、β-谷甾醇乙酸酯（4）、5-（羟甲基）糠醛（5）、壬二酸（6）、β-胡萝卜苷（7）、环（苯丙氨酸-酪氨酸）（8）、环（酪氨酸-酪氨酸）（9）、6-甲基柠檬酸（10）、1,5-二甲基柠檬酸（11）、柠檬酸三甲酯（12）。
化合物3-12首次从该植物中分离得到，环二肽首次从薯蓣科植物中分离得到；化合物9为新天然产物。
