Pearce J M S
Emeritus Consultant Neurologist, Department of Neurology, Hull Royal Infirmary, Hull, UK.
Eur Neurol. 2008;60(6):312-5. doi: 10.1159/000159929. Epub 2008 Oct 3.
Symptomatic palatal tremor is caused by a lesion in the triangle of Guillain and Mollaret and is associated with hypertrophic olivary degeneration that has multiple causes. Essential palatal tremor has no currently demonstrable cause and no accompanying physical or radiological signs. But it is probable that an organic genesis will become apparent. I suggest that some examples of palatal tremor may depend on an 'upper motor neurone type', i.e. supranuclear, lesion in the striatum or rostral brainstem releasing medullary activation with denervation hypersensitivity of olivary neurones.
症状性腭震颤由 Guillain 和 Mollaret 三角区的病变引起,并与多种原因导致的橄榄体肥大性变性相关。原发性腭震颤目前尚无明确病因,也无伴随的体格检查或影像学体征。但很可能其器质性病因会逐渐显现。我认为某些腭震颤的病例可能取决于一种“上运动神经元类型”,即纹状体或延髓上部脑干的核上病变,导致延髓激活,同时橄榄体神经元出现去神经超敏反应。