Sumana Gurunath, Dadhwal Vatsla, Deka Deepika, Mittal Suneeta
Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences, New Delhi, India.
J Obstet Gynaecol Res. 2008 Oct;34(5):801-4. doi: 10.1111/j.1447-0756.2008.00853.x.
Non-cirrhotic portal hypertension (NCPH) is a common cause of portal hypertension in developing countries, especially Asia. Recent data have shown near-normal reproductive function and good pregnancy outcome for NCPH compared with cirrhosis. The aim of the present study was to evaluate complications during pregnancy and pregnancy outcome in women with NCPH.
Twelve pregnancies in five patients with NCPH were evaluated.
In the present study, 20% of patients had hematemesis during pregnancy that was managed successfully. Four patients (80%) had severe anemia (hemoglobin 6-7 g%) and three (60%) had thrombocytopenia. There were no preterm births. Of a total of nine live births, six were vaginal deliveries and three were delivered by Cesarean section (performed for obstetric indications). Four babies (44%) were small for gestational age (SGA).
The results show that patients with NCPH have normal fertility, no apparent increase in the incidence of hematemesis during pregnancy, an increased incidence of SGA babies and no indication for elective Cesarean delivery.
非肝硬化性门静脉高压（NCPH）是发展中国家尤其是亚洲门静脉高压的常见病因。近期数据显示，与肝硬化相比，NCPH患者的生殖功能接近正常，妊娠结局良好。本研究的目的是评估NCPH女性患者孕期并发症及妊娠结局。
对5例NCPH患者的12次妊娠进行评估。
在本研究中，20%的患者在孕期发生呕血，但均成功处理。4例（80%）患者出现严重贫血（血红蛋白6 - 7 g%），3例（60%）出现血小板减少。无早产发生。在总共9例活产中，6例经阴道分娩，3例剖宫产（因产科指征）。4例婴儿（44%）小于胎龄（SGA）。
结果表明，NCPH患者生育能力正常，孕期呕血发生率无明显增加，SGA婴儿发生率增加，且无选择性剖宫产指征。
