鉴定一种新的医院获得性克隆复合体17粪肠球菌分离株特有的基因组岛。
Identification of a novel genomic island specific to hospital-acquired clonal complex 17 Enterococcus faecium isolates.
作者信息
Heikens Esther, van Schaik Willem, Leavis Helen L, Bonten Marc J M, Willems Rob J L
机构信息
Department of Medical Microbiology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.
出版信息
Appl Environ Microbiol. 2008 Nov;74(22):7094-7. doi: 10.1128/AEM.01378-08. Epub 2008 Oct 3.
Abstract
Hospital-acquired clonal complex 17 (CC17) Enterococcus faecium strains are genetically distinct from indigenous strains and are enriched with resistance genes and virulence genes. We identified a genomic island in CC17 E. faecium tentatively encoding a metabolic pathway involved in carbohydrate transport and metabolism, which may provide a competitive advantage over the indigenous E. faecium microbiota.
摘要
医院获得性克隆复合体17（CC17）粪肠球菌菌株在基因上与本地菌株不同，并且富含耐药基因和毒力基因。我们在CC17粪肠球菌中鉴定出一个基因组岛，初步编码一条参与碳水化合物运输和代谢的代谢途径，这可能使其相对于本地粪肠球菌微生物群具有竞争优势。
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