可卡因诱导的脑血管炎的血氧水平依赖性功能磁共振成像脑血管反应性研究结果
BOLD-MRI cerebrovascular reactivity findings in cocaine-induced cerebral vasculitis.
作者信息
Han Jay S, Mandell Daniel M, Poublanc Julien, Mardimae Alexandra, Slessarev Marat, Jaigobin Cheryl, Fisher Joseph A, Mikulis David J
机构信息
Department of Physiology at the University of Toronto, Toronto, ON, Canada.
出版信息
Nat Clin Pract Neurol. 2008 Nov;4(11):628-32. doi: 10.1038/ncpneuro0918. Epub 2008 Oct 7.
BACKGROUND
An 18-year-old woman presented to a regional stroke center with dysphasia and right hemiparesis 2 days after consuming alcohol and inhaling cannabis and -- for the first time -- cocaine.
INVESTIGATIONS
Physical examination, blood tests for inflammatory markers, vasculitis and toxicology screen, echocardiography, electrocardiography, CT scanning, brain MRI, magnetic resonance angiography, magnetic resonance vessel wall imaging, catheter angiography, and correlation of blood oxygen level-dependent (BOLD)-MRI signal intensity with changes in end-tidal partial pressure of carbon dioxide.
DIAGNOSIS
Cocaine-induced cerebral vasculitis.
MANAGEMENT
No specific therapy was initiated. The patient's vital signs and neurological status were monitored during her admission. Follow-up medical imaging was performed after the patient's discharge from hospital.
背景
一名18岁女性在饮酒、吸食大麻以及首次吸食可卡因两天后，因言语困难和右侧偏瘫被送至一家地区性卒中中心。
检查
体格检查、检测炎症标志物、血管炎及进行毒理学筛查的血液检测、超声心动图、心电图、CT扫描、脑部MRI、磁共振血管造影、磁共振血管壁成像、导管血管造影，以及血液氧水平依赖（BOLD）-MRI信号强度与呼气末二氧化碳分压变化的相关性分析。
诊断
可卡因诱发的脑血管炎。
治疗
未开始进行特定治疗。患者住院期间监测其生命体征和神经状态。患者出院后进行了随访医学成像检查。
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