Cheung C Y, Chan H W, Liu Y L, Chan Y H, Wong H S, Chak W L, Choi K S, Chau K F, Li C S
Renal Unit, Queen Elizabeth Hospital, 30 Gascoigne Road, Hong Kong.
Hong Kong Med J. 2008 Oct;14(5):379-84.
To investigate the prevalence of metabolic syndrome in Chinese renal transplant recipients, using two different sets of diagnostic criteria.
Cross-sectional study.
Regional hospital, Hong Kong.
All Chinese patients who received solitary living-related or cadaveric kidney transplantation from 1 July 1997 to 31 December 2005 in our hospital with follow-up of more than 6 months were recruited. The diagnosis of metabolic syndrome was made according to the National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATPIII) criteria and the International Diabetes Federation criteria.
Using the modified (Asian) NCEP-ATPIII criteria, a total of 39 (32%) of 121 patients had metabolic syndrome, which included 20/69 (29%) of the males and 19/52 (37%) of the females. Using the International Diabetes Federation criteria, metabolic syndrome was diagnosed in 26% of the patients, 22% in males and 31% in females. In our patients, the most common component of metabolic syndrome was hypertension and the least common was low high-density-lipoprotein-cholesterol level. Low high-density-lipoprotein-cholesterol levels were significantly more common in female patients.
This study shows that there is a high prevalence of metabolic syndrome in our Chinese renal transplant recipients.
采用两套不同的诊断标准，调查中国肾移植受者代谢综合征的患病率。
横断面研究。
香港地区医院。
招募了1997年7月1日至2005年12月31日在我院接受活体亲属或尸体肾移植且随访超过6个月的所有中国患者。代谢综合征的诊断依据美国国家胆固醇教育计划成人治疗专家组第三次报告（NCEP-ATPIII）标准和国际糖尿病联盟标准。
采用修订后的（亚洲）NCEP-ATPIII标准，121例患者中有39例（32%）患有代谢综合征，其中男性20/69例（29%），女性19/52例（37%）。采用国际糖尿病联盟标准，26%的患者被诊断为代谢综合征，男性为22%，女性为31%。在我们的患者中，代谢综合征最常见的组成部分是高血压，最不常见的是高密度脂蛋白胆固醇水平降低。高密度脂蛋白胆固醇水平降低在女性患者中更为常见。
本研究表明，中国肾移植受者中代谢综合征的患病率很高。
