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[一例因癌性腹膜炎导致身体状况较差的胰腺癌尸检病例,采用低剂量5-氟尿嘧啶与奥曲肽持续输注成功治疗]

[An autopsy case of pancreatic cancer with poor performance status due to peritonitis carcinomatosa treated successfully with continuous infusion of low-dose 5-FU with octreotide].

作者信息

Mouri Hisatsugu, Tsuchiyama Tomoya, Ohtsubo Koshiro, Kayahara Masato, Ohta Tetsuo, Kitagawa Satoshi, Minato Hiroshi, Watanabe Hiroyuki

机构信息

Department of Internal Medicine and Medical Oncology, Cancer Research Institute, Kanazawa University.

出版信息

Nihon Shokakibyo Gakkai Zasshi. 2008 Oct;105(10):1529-35.

Abstract

A 60-year-old man with pancreatic cancer was admitted due to massive ascites in the course of gemcitabine treatment. Cachexic condition progressed due to peritonitis carcinomatosa. Continuous infusion of low dose 5-FU with octreotide was carefully started. Almost all of ascites disappeared after 4 courses of treatment and his general condition markedly improved. This patient died of pneumonia about 13 months after diagnosis of peritonitis carcinomatosa. Autopsy was undergone, and the effect of chemotherapy was confirmed.

摘要

一名60岁的胰腺癌男性患者在接受吉西他滨治疗期间因大量腹水入院。由于癌性腹膜炎,恶病质状态进展。开始谨慎地持续输注低剂量5-氟尿嘧啶并联合奥曲肽。4个疗程的治疗后几乎所有腹水消失,患者的一般状况明显改善。该患者在诊断为癌性腹膜炎约13个月后死于肺炎。进行了尸检,化疗效果得到证实。

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