Adams J, Fantner G E, Fisher L W, Hansma P K
Department of Physics, Broida Hall, University of California, Santa Barbara, CA 93106, USA.
Nanotechnology. 2008 Sep 24;19(38):384008. doi: 10.1088/0957-4484/19/38/384008.
The fracture resistance of biomineralized tissues such as bone, dentin, and abalone is greatly enhanced through the nanoscale interactions of stiff inorganic mineral components with soft organic adhesive components. A proper understanding of the interactions that occur within the organic component, and between the organic and inorganic components, is therefore critical for a complete understanding of the mechanics of these tissues. In this paper, we use Atomic Force Microscope (AFM) force spectroscopy and dynamic force spectroscopy to explore the effect of ionic interactions within a nanoscale system consisting of networks of Dentin Matrix Protein 1 (DMP1) (a component of both bone and dentin organic matrix), a mica surface, and an AFM tip. We find that DMP1 is capable of dissipating large amounts of energy through an ion-mediated mechanism, and that the effectiveness increases with increasing ion valence.
诸如骨骼、牙本质和鲍鱼壳等生物矿化组织的抗断裂能力，通过坚硬的无机矿物成分与柔软的有机黏附成分之间的纳米级相互作用得到了极大增强。因此，正确理解有机成分内部以及有机和无机成分之间发生的相互作用，对于全面理解这些组织的力学性能至关重要。在本文中，我们使用原子力显微镜（AFM）力谱和动态力谱，来探究在由牙本质基质蛋白1（DMP1）（骨骼和牙本质有机基质的一种成分）网络、云母表面和AFM探针组成的纳米级系统中离子相互作用的影响。我们发现，DMP1能够通过离子介导机制耗散大量能量，并且其有效性随着离子价态的增加而提高。
