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齿状突骨折的手术治疗与保守治疗对比

Surgical versus conservative management for odontoid fractures.

作者信息

Shears Emma, Armitstead Christopher P

机构信息

Spinal Unit, Royal Orthopaedic Hospital, Bristol Road, Northfield, Birmingham, West Midlands, UK, B31 2AP.

出版信息

Cochrane Database Syst Rev. 2008 Oct 8;2008(4):CD005078. doi: 10.1002/14651858.CD005078.pub2.

Abstract

BACKGROUND

Fractures of the odontoid process of the second cervical vertebra can result in instability, neurological damage and death. Treatment includes conservative management (external immobilisation devices) or surgical treatment (internal fixation by posterior fusion or anterior screw fixation).

OBJECTIVES

To compare surgical with conservative treatment for fractures of the odontoid process.

SEARCH STRATEGY

We searched the Cochrane Bone, Joint and Muscle Trauma Group Specialised Register (February 2008), the Cochrane Central Register of Controlled Trials (The Cochrane Library 2008, Issue 1), MEDLINE (1966 to February 2008), EMBASE (1988 to February 2008), LILACS (accessed February 2008), reference lists of articles and registries of ongoing trials.

SELECTION CRITERIA

Randomised and quasi-randomised controlled trials comparing surgical versus conservative management of odontoid fractures.

DATA COLLECTION AND ANALYSIS

Two review authors independently examined the search results to identify trials for inclusion.

MAIN RESULTS

We did not identify any studies that met our inclusion criteria. We excluded one ongoing and registered study that is comparing surgery versus conservative treatment because it does not involve randomisation of treatment allocation.

AUTHORS' CONCLUSIONS: There is no evidence available from adequately controlled trials to inform the decision on whether the surgical treatment of odontoid fractures gives a better outcome. A sufficiently powered good quality multicentre randomised controlled trial comparing surgery versus conservative treatment is warranted.

摘要

背景

第二颈椎齿突骨折可导致不稳定、神经损伤甚至死亡。治疗方法包括保守治疗(外部固定装置)或手术治疗(后路融合内固定或前路螺钉固定)。

目的

比较齿突骨折的手术治疗与保守治疗。

检索策略

我们检索了Cochrane骨、关节和肌肉创伤组专业注册库(2008年2月)、Cochrane对照试验中心注册库(Cochrane图书馆2008年第1期)、MEDLINE(1966年至2008年2月)、EMBASE(1988年至2008年2月)、LILACS(2008年2月检索)、文章参考文献列表及正在进行的试验注册库。

选择标准

比较齿突骨折手术治疗与保守治疗的随机和半随机对照试验。

数据收集与分析

两位综述作者独立检查检索结果以确定纳入试验。

主要结果

我们未找到任何符合纳入标准的研究。我们排除了一项正在进行并已注册的比较手术与保守治疗的研究,因为它未涉及治疗分配的随机化。

作者结论

尚无充分对照试验的证据可用于指导关于齿突骨折手术治疗是否能带来更好疗效的决策。有必要开展一项足够有力的高质量多中心随机对照试验来比较手术与保守治疗。

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