Kantorová E
Oddĕlení lékarské genetiky, KUNZ, Ceské Budĕjovice.
Cesk Pediatr. 1991 Jan;46(1):23-5.
The investigation was focused on assessment of the frequency of risk factors for the development of ischaemic heart disease (IHD)--hyperlipoproteinaemia, smoking, arterial hypertension and obesity--in the offspring of subjects suffering from the disease before the age of 55 years. Among grade I 126 offspring they recorded in 6.4% hyperlipoproteinaemia, in 29.4% smoking, in 2.4% arterial hypertension and in 16.7% obesity. The author draws attention to the fact that almost 40% of the offspring under 35 years of age of subjects with a history of early IHD have at least one risk factor for the development of the disease. These subjects are a high group which should be screened and followed up within the framework of primary prevention of cardiovascular diseases.
该研究聚焦于评估55岁前患有缺血性心脏病(IHD)的患者后代中,缺血性心脏病发病风险因素——高脂蛋白血症、吸烟、动脉高血压和肥胖——的出现频率。在一级亲属的126名后代中,他们记录到高脂蛋白血症的发生率为6.4%,吸烟为29.4%,动脉高血压为2.4%,肥胖为16.7%。作者提请注意,有早期缺血性心脏病病史的患者中,近40%的35岁以下后代至少有一个该病发病的风险因素。这些对象属于高危人群,应在心血管疾病一级预防的框架内进行筛查和随访。