Wallin Olof, Söderberg Johan, Grankvist Kjell, Jonsson P Andreas, Hultdin Johan
Department of Medical Biosciences, Clinical Chemistry, Umeå University, Umeå, Sweden.
Clin Chem Lab Med. 2008;46(10):1443-9. doi: 10.1515/CCLM.2008.288.
Pneumatic tube transport of blood samples reduces turnaround times and labour. However, the preanalytical effects on new clinical chemistry parameters and instruments are not fully known. The aim of this study was to evaluate the effect of pneumatic tube transport on haematology and coagulation parameters, including platelet function with PFA-100, and global coagulation with a thromboelastograph.
Paired venous blood samples from healthy volunteers were obtained before and after 1 week of treatment with acetylsalicylic acid. One sample was transported by pneumatic tube transport, while the other remained in the laboratory.
No preanalytical effect of pneumatic tube transport could be seen for most haematology and coagulation parameters, as well as analysis with PFA-100. For the thromboelastographic analysis, time to clot formation was shorter (-16%, p=0.037) in the transported samples. Treatment with acetylsalicylic acid had no effect on the majority of the test results.
Pneumatic tube transport does not introduce preanalytical errors when transporting samples for analysis of routine haematology, coagulation parameters and platelet function with the PFA-100. We recommend manual transport of samples for analysis with thromboelastographic techniques.
气动管道输送血样可缩短周转时间并减少人力。然而，其对新的临床化学参数和仪器的分析前影响尚不完全清楚。本研究的目的是评估气动管道输送对血液学和凝血参数的影响，包括使用血小板功能分析仪（PFA-100）检测血小板功能以及使用血栓弹力图仪检测整体凝血情况。
从健康志愿者身上采集配对的静脉血样，分别在服用乙酰水杨酸治疗1周前后采集。一份血样通过气动管道输送，另一份留在实验室。
对于大多数血液学和凝血参数以及使用PFA-100进行的分析，未观察到气动管道输送的分析前影响。对于血栓弹力图分析，输送样本的凝血形成时间较短（缩短16%，p = 0.037）。乙酰水杨酸治疗对大多数检测结果无影响。
在输送用于常规血液学、凝血参数分析及使用PFA-100检测血小板功能的样本时，气动管道输送不会引入分析前误差。我们建议使用血栓弹力图技术分析的样本采用手工输送。
