Carter S R, Grimer R J, Sneath R S
Birmingham Bone Tumour Treatment Service, Royal Orthopaedic Hospital, England.
Clin Orthop Relat Res. 1991 Sep(270):45-51.
Since the inception of the authors' facility, 365 patients with osteogenic sarcoma have been treated. While other facilities were surgically treating patients with primary amputation, this facility attempted limb-salvage surgery. The majority of patients being treated with limb-salvage surgery had the resected bone replaced by a metallic endoprosthetic replacement. The emphasis on conservative surgery led to the development of growing endoprosthetic replacements with the first being used in 1975. The cumulative survival of those patients with Stage 2 osteosarcoma treated at this facility between 1977 and 1984 is 48% at five years.
自作者所在机构成立以来，已治疗了365例骨肉瘤患者。当其他机构采用一期截肢手术治疗患者时，该机构尝试进行保肢手术。大多数接受保肢手术治疗的患者，其切除的骨头被金属内置假体替代。对保守手术的重视促使了可延长内置假体的发展，首个此类假体于1975年投入使用。1977年至1984年期间，在该机构接受治疗的2期骨肉瘤患者的五年累计生存率为48%。
