Cara del Rosal J A, Cañadell J
Department of Orthopaedic Surgery, University Clinic, Faculty of Medicine, University of Navarre, Pamplona, Spain.
Int Orthop. 1994;18(6):375-8. doi: 10.1007/BF00187086.
Seventy-eight consecutive patients with stage IIB osteosarcoma of the appendicular skeleton, treated between 1982 and 1992, were studied to determine whether the technique of biopsy affected the prognosis for long term survival. The risk of local recurrence was significant (p < 0.02) after open biopsy, as was the poor response to chemotherapy (p < 0.05) after percutaneous biopsy. We recommend percutaneous biopsy, if possible, when an osteosarcoma is suspected.
对1982年至1992年间接受治疗的78例连续性四肢骨骼IIB期骨肉瘤患者进行研究，以确定活检技术是否会影响长期生存预后。切开活检后局部复发风险显著（p<0.02），经皮活检后对化疗反应不佳（p<0.05）。如果怀疑骨肉瘤，我们建议尽可能采用经皮活检。
