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本文引用的文献

1
Vibrio parahaemolyticus orchestrates a multifaceted host cell infection by induction of autophagy, cell rounding, and then cell lysis.副溶血性弧菌通过诱导自噬、细胞变圆,进而导致细胞裂解来精心策划多方面的宿主细胞感染。
Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12497-502. doi: 10.1073/pnas.0802773105. Epub 2008 Aug 19.
2
Pseudomonas aeruginosa uses type III secretion system to kill biofilm-associated amoebae.铜绿假单胞菌利用III型分泌系统杀死与生物膜相关的变形虫。
ISME J. 2008 Aug;2(8):843-52. doi: 10.1038/ismej.2008.47. Epub 2008 May 15.
3
Pseudomonas aeruginosa utilises its type III secretion system to kill the free-living amoeba Acanthamoeba castellanii.铜绿假单胞菌利用其三型分泌系统杀死自由生活的变形虫——卡氏棘阿米巴。
J Eukaryot Microbiol. 2008 May-Jun;55(3):235-43. doi: 10.1111/j.1550-7408.2008.00311.x.
4
Vibrios in association with sedimentary crustaceans in three beaches of the northern Adriatic Sea (Italy).意大利亚得里亚海北部三个海滩中与沉积甲壳类动物相关的弧菌。
Mar Pollut Bull. 2008 Mar;56(3):574-9. doi: 10.1016/j.marpolbul.2007.12.011. Epub 2008 Feb 20.
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Inter-kingdom signalling: communication between bacteria and their hosts.跨界信号传导:细菌与其宿主之间的通讯
Nat Rev Microbiol. 2008 Feb;6(2):111-20. doi: 10.1038/nrmicro1836.
6
Arp2/3-independent assembly of actin by Vibrio type III effector VopL.弧菌III型效应蛋白VopL介导的不依赖Arp2/3的肌动蛋白组装
Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):17117-22. doi: 10.1073/pnas.0703196104. Epub 2007 Oct 17.
7
Vibrio cholerae O1 strains are facultative intracellular bacteria, able to survive and multiply symbiotically inside the aquatic free-living amoeba Acanthamoeba castellanii.霍乱弧菌O1菌株是兼性胞内细菌,能够在水生自由生活的变形虫——卡氏棘阿米巴中进行共生生存和繁殖。
FEMS Microbiol Ecol. 2007 Apr;60(1):33-9. doi: 10.1111/j.1574-6941.2006.00254.x.
8
Acanthamoeba: could it be an environmental host of Shigella?棘阿米巴:它会是志贺氏菌的环境宿主吗?
Exp Parasitol. 2007 Feb;115(2):181-6. doi: 10.1016/j.exppara.2006.08.002. Epub 2006 Sep 15.
9
Detection of free-living and plankton-bound vibrios in coastal waters of the Adriatic Sea (Italy) and study of their pathogenicity-associated properties.亚得里亚海(意大利)沿海水域中自由生活和浮游生物附着的弧菌检测及其致病性相关特性研究。
Environ Microbiol. 2006 Jul;8(7):1299-305. doi: 10.1111/j.1462-2920.2006.01011.x.
10
Acanthamoeba: biology and increasing importance in human health.棘阿米巴:生物学特性及其在人类健康中日益重要的地位
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卡氏棘阿米巴促进副溶血性弧菌的存活。

Acanthamoeba castellanii promotes the survival of Vibrio parahaemolyticus.

作者信息

Laskowski-Arce Michelle A, Orth Kim

机构信息

Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA.

出版信息

Appl Environ Microbiol. 2008 Dec;74(23):7183-8. doi: 10.1128/AEM.01332-08. Epub 2008 Oct 10.

DOI:10.1128/AEM.01332-08
PMID:18849458
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2592933/
Abstract

Vibrio parahaemolyticus is a food-borne pathogen that naturally inhabits both marine and estuarine environments. Free-living protozoa exist in similar aquatic environments and function to control bacterial numbers by grazing on free-living bacteria. Protozoa also play an important role in the survival and spread of some pathogenic species of bacteria. We investigated the interaction between the protozoan Acanthamoeba castellanii and the bacterium Vibrio parahaemolyticus. We found that Acanthamoeba castellanii does not prey on Vibrio parahaemolyticus but instead secretes a factor that promotes the survival of Vibrio parahaemolyticus in coculture. These studies suggest that protozoa may provide a survival advantage to an extracellular pathogen in the environment.

摘要

副溶血性弧菌是一种食源性病原体,自然栖息于海洋和河口环境。自由生活的原生动物存在于类似的水生环境中,通过捕食自由生活的细菌来控制细菌数量。原生动物在某些致病细菌物种的生存和传播中也起着重要作用。我们研究了原生动物卡氏棘阿米巴与副溶血性弧菌之间的相互作用。我们发现卡氏棘阿米巴并不捕食副溶血性弧菌,而是分泌一种因子,该因子能促进副溶血性弧菌在共培养中的存活。这些研究表明,原生动物可能为环境中的细胞外病原体提供生存优势。