Herrero Ana, Mendoza M Carmen, Rodicio Rosaura, Rodicio M Rosario
Departamento de Biología Funcional (Area de Microbiología) and Instituto Universitario de Biotecnología de Asturias, Universidad de Oviedo, 33006 Oviedo, Spain.
Antimicrob Agents Chemother. 2008 Dec;52(12):4514-7. doi: 10.1128/AAC.00563-08. Epub 2008 Oct 13.
pUO-StVR2 is a virulence-resistance plasmid which originated from pSLT of Salmonella enterica serovar Typhimurium through acquisition of a complex resistance island, flanked by regions that provide a toxin-antitoxin system and an iron uptake system. The presence of resistance and virulence determinants on the same plasmid allows coselection of both properties, potentially increasing health risks.
pUO-StVR2是一种毒力抗性质粒,它起源于鼠伤寒沙门氏菌的pSLT,通过获得一个复杂的抗性岛,该抗性岛两侧是提供毒素-抗毒素系统和铁摄取系统的区域。同一质粒上存在抗性和毒力决定因素使得这两种特性能够共同选择,可能增加健康风险。