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[由伯氏考克斯体(Q热)引起的心内膜炎:一种罕见或诊断不足的疾病?病例报告]

[Endocarditis due to Coxiella burnetii (Q fever): a rare or underdiagnosed disease? Case report].

作者信息

Siciliano Rinaldo Focaccia, Ribeiro Henrique Barbosa, Furtado Remo Holanda de Mendonça, Castelli Jussara Bianchi, Sampaio Roney Orismar, Santos Fabiana Cristina Pereira dos, Colombo Silvia, Grinberg Max, Strabelli Tânia Mara Varejão

机构信息

Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo.

出版信息

Rev Soc Bras Med Trop. 2008 Jul-Aug;41(4):409-12. doi: 10.1590/s0037-86822008000400017.

Abstract

Q fever is a zoonosis of worldwide distribution that is caused by Coxiella burnetii. However, reports of this disease in Brazil are rare. Seroepidemiological studies have shown relatively high frequencies of antibodies against Coxiella burnetii in populations with occupational exposure. In humans, it can be manifested clinically as acute or chronic disease. Endocarditis is the most frequent chronic form of Q fever and the form with the greatest morbidity and mortality. We report a severe case of endocarditis due to Coxiella burnetii acquired in Brazil that had a fatal outcome, despite specific antibiotic therapy and valve surgery treatment.

摘要

Q热是一种由伯氏考克斯体引起的、呈全球分布的人畜共患病。然而,巴西关于这种疾病的报告很少。血清流行病学研究表明,职业暴露人群中抗伯氏考克斯体抗体的频率相对较高。在人类中,它可临床上表现为急性或慢性疾病。心内膜炎是Q热最常见的慢性形式,也是发病率和死亡率最高的形式。我们报告了一例在巴西感染伯氏考克斯体导致的心内膜炎严重病例,尽管进行了特异性抗生素治疗和瓣膜手术治疗,但仍导致了致命的结果。

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