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电刀锥切术后宫颈狭窄

Cervical stenosis following electrosurgical conization.

作者信息

Monteiro Aparecida Cristina Sampaio, Russomano Fábio Bastos, Camargo Maria José de, Silva Kátia Silveira da, Veiga Fernanda Rangel, Oliveira Rebecca Guimarães

机构信息

Department of Gynecology and Obstetrics, Cervical Pathology Sector, Instituto Fernandes Figueira, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.

出版信息

Sao Paulo Med J. 2008 Jul;126(4):209-14. doi: 10.1590/s1516-31802008000400002.

DOI:10.1590/s1516-31802008000400002
PMID:18853028
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11025978/
Abstract

CONTEXT AND OBJECTIVE

Cervical stenosis is a postoperative complication of procedures for treating preinvasive lesions of the cervix and takes on particular importance due to the clinical repercussions associated with it. Furthermore, it causes limitations in relation to cytological and colposcopic follow-up. The aim here was to assess the incidence of cervical stenosis among a cohort of patients who underwent electrosurgical conization and to identify possible prognostic factors associated with its occurrence.

DESIGN AND SETTING

Retrospective study at Gynecology and Obstetrics Department, Instituto Fernandes Figueira, Rio de Janeiro.

METHODS

This was an observational study among a cohort of patients who underwent electrosurgical conization of the uterine cervix. The possible predictive variables were analyzed as bivariate means between the groups with and without stenosis. We also calculated the incidence density rate ratio for cervical stenosis in relation to each possible predictive variable and the respective confidence intervals (95%). Levels of 5% were considered significant.

RESULTS

274 patients who underwent electrosurgical conization of the uterine cervix with a minimum follow-up period of six months were included. The crude incidence of cervical stenosis was 7.66% and the incidence density was 3.3/1,000 patients-month.

CONCLUSIONS

We did not find associations between the variables for stenosis. However, we observed borderline significance levels relating to hemorrhagic complications before and after the operation (p = 0.089).

摘要

背景与目的

宫颈狭窄是宫颈浸润前病变治疗手术的术后并发症,因其相关的临床影响而具有特殊重要性。此外,它在细胞学和阴道镜随访方面造成限制。本研究旨在评估接受电刀锥切术的一组患者中宫颈狭窄的发生率,并确定与其发生相关的可能预后因素。

设计与地点

在里约热内卢费尔南德斯·菲格雷拉研究所妇产科进行的回顾性研究。

方法

这是一项对接受子宫颈电刀锥切术的一组患者的观察性研究。对有狭窄和无狭窄组之间的可能预测变量进行双变量分析。我们还计算了宫颈狭窄相对于每个可能预测变量的发病率密度率比及其各自的置信区间(95%)。5%的水平被认为具有统计学意义。

结果

纳入274例接受子宫颈电刀锥切术且最短随访期为6个月的患者。宫颈狭窄的粗发病率为7.66%,发病率密度为3.3/1000患者·月。

结论

我们未发现狭窄变量之间存在关联。然而,我们观察到手术前后出血并发症的临界显著性水平(p = 0.089)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/722d/11025978/951321b900bf/1806-9460-spmj-126-04-209-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/722d/11025978/951321b900bf/1806-9460-spmj-126-04-209-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/722d/11025978/951321b900bf/1806-9460-spmj-126-04-209-gf01.jpg

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本文引用的文献

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Laser CO2 conization in postmenopausal age: risk of cervical stenosis and unsatisfactory follow-up.绝经后年龄行激光二氧化碳锥切术:宫颈管狭窄风险及随访结果不理想
Gynecol Oncol. 2005 Mar;96(3):771-5. doi: 10.1016/j.ygyno.2004.11.012.
2
Hysterectomy in women with cervical stenosis. Surgical indications and pathology.宫颈狭窄女性的子宫切除术。手术指征与病理
J Reprod Med. 2003 Sep;48(9):672-6.
3
Long-term outcome of a randomized study comparing three techniques of conization: cold knife, laser, and LEEP.一项比较三种锥切技术(冷刀、激光和环形电切术)的随机研究的长期结果
硅胶导管治疗微创宫颈癌患者锥切术后宫颈狭窄:一例报告
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The effects of different instruments and suture methods of conization for cervical lesions.不同器械和缝合方法在宫颈病变锥切术中的效果。
Sci Rep. 2019 Dec 13;9(1):19114. doi: 10.1038/s41598-019-55786-4.
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Levonorgestrel-releasing intrauterine system placement for severe uterine cervical stenosis after conization: two case reports.左炔诺孕酮宫内节育系统置入治疗锥切术后严重宫颈管狭窄:两例病例报告
J Med Case Rep. 2016 Mar 9;10:56. doi: 10.1186/s13256-016-0831-9.
6
Conization Using an Electrosurgical Knife for Cervical Intraepithelial Neoplasia and Microinvasive Carcinoma.使用电刀对宫颈上皮内瘤变和微浸润癌进行锥形切除术。
PLoS One. 2015 Jul 8;10(7):e0131790. doi: 10.1371/journal.pone.0131790. eCollection 2015.
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Risk of preterm delivery associated with prior treatment of cervical precancerous lesion according to the depth of the cone.根据锥切深度,与宫颈癌前病变治疗相关的早产风险。
Dis Markers. 2013;35(6):721-6. doi: 10.1155/2013/686027. Epub 2013 Nov 13.
Eur J Obstet Gynecol Reprod Biol. 2003 Feb 10;106(2):214-8. doi: 10.1016/s0301-2115(02)00245-2.
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Treating intraepithelial lesions of the uterine cervix by laser CO2. Evaluation of the past, appraisal for the future.二氧化碳激光治疗子宫颈上皮内病变。回顾过去,展望未来。
Eur J Gynaecol Oncol. 2002;23(5):463-8.
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[Complications, sequellae and outcome of cervical conizations: evaluation of three surgical technics].[宫颈锥切术的并发症、后遗症及结局:三种手术技术的评估]
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6
Risk factors for cervical stenosis after laser cone biopsy.激光锥形活检术后宫颈管狭窄的危险因素。
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Risk factors for cervical stenosis after loop electrocautery excision procedure.
Obstet Gynecol. 2000 Nov;96(5 Pt 1):657-60.
8
Risk of cervical stenosis after large loop excision or laser conization.大环状切除术或激光锥切术后宫颈管狭窄的风险。
Obstet Gynecol. 1996 Dec;88(6):933-8. doi: 10.1016/S0029-7844(96)00331-6.
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Loop diathermy and cold-knife conization in patients with cervical intraepithelial neoplasia: a comparative study.宫颈上皮内瘤变患者的环形电切术与冷刀锥切术:一项对比研究
J Korean Med Sci. 1995 Aug;10(4):281-6. doi: 10.3346/jkms.1995.10.4.281.
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Electrosurgical loop excision of the cervical transformation zone: the experience of family physicians.宫颈转化区的电外科环形切除术:家庭医生的经验
J Fam Pract. 1995 Oct;41(4):337-44.