Prout M N, Richards M J, Chung K J, Joo P, Davis H L
Cancer. 1977 Jan;39(1):62-5. doi: 10.1002/1097-0142(197701)39:1<62::aid-cncr2820390112>3.0.co;2-j.
Two children with Wilms' tumor and prior thoracic radiation developed congestive heart failure at cumulative adriamycin doses of 350 mg/m2 and 400 mg/m2. Details of these two cases and a summary of previously reported adriamycin cardiotoxicity in children are presented. Dose recommendations and predictive tests are discussed.