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大剂量阿托品持续输注用于有机磷化合物中毒的治疗

Continuous infusion of high doses of atropine in the management of organophosphorus compound poisoning.

作者信息

Ram J S, Kumar S S, Jayarajan A, Kuppuswamy G

机构信息

Department of Medicine, St Martha's Hospital, Bangalore.

出版信息

J Assoc Physicians India. 1991 Feb;39(2):190-3.

PMID:1885485
Abstract

Forty five cases of organophosphorus poisoning were studied to evaluate the results of continuous infusion of high doses of atropine as against the conventional intermittent therapy. A statistically significant reduction in mortality (23.5% to 8.8%; p less than 0.05) was evident in this study as compared to previous years. Pseudocholinesterase levels below 10% of normal were associated with a poor prognosis and increased mortality.

摘要

对45例有机磷中毒病例进行了研究,以评估大剂量阿托品持续输注与传统间歇性治疗的效果。与前几年相比,本研究中死亡率有统计学意义的显著降低(从23.5%降至8.8%;p<0.05)。假性胆碱酯酶水平低于正常水平的10%与预后不良和死亡率增加相关。

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