Requena L, Sánchez M, Requena I, Alegre V, Sánchez Yus E
Department of Dermatology, Hospital Clínico San Carlos, Facultad de Medicina, Universidad Complutense, Madrid, Spain.
J Dermatol Surg Oncol. 1991 Aug;17(8):656-60. doi: 10.1111/j.1524-4725.1991.tb01315.x.
Squamous cell carcinomas (SCCs) usually show a standard histopathologic picture only varying with regard to their degree of differentiation. The authors describe a case of clear cell SCC that was studied by light and electron microscopy. The clear cells showed an empty cytoplasm that was periodic acid-Schiff and alcian blue negative. By electron microscopy these cytoplasms consisted of empty spaces and were not surrounded by membranes, which would be consistent with lipid vacuoles. The differential diagnosis of this uncommon variant of SCC requires consideration of other clear cell tumors.
鳞状细胞癌（SCC）通常呈现出标准的组织病理学图像，仅在分化程度上有所不同。作者描述了一例经光镜和电镜研究的透明细胞SCC病例。透明细胞显示出空泡状胞质，对过碘酸希夫反应和阿尔辛蓝染色呈阴性。通过电镜观察，这些胞质由空泡组成，且没有被膜包围，这与脂质空泡相符。对这种不常见的SCC变异型进行鉴别诊断时需要考虑其他透明细胞瘤。
