Howe N R, Lang P G
Department of Dermatology, Medical University of South Carolina, Charleston 29425.
J Dermatol Surg Oncol. 1991 Oct;17(10):779-83. doi: 10.1111/j.1524-4725.1991.tb03259.x.
Four patients with squamous cell carcinomas (SCCs) presenting as subcutaneous nodules of the head were referred for Mohs micrographic surgery. In each case initial histologic sections showed no connection between the tumor and epidermis, raising the possibility that each was a metastasis from an occult SCC. Careful searches for occult SCCs were unrevealing. Subsequent step sections through the entire tumors revealed narrow connections to the overlying epidermis in three of the four cases.
4例表现为头部皮下结节的鳞状细胞癌（SCC）患者被转诊至莫氏显微外科手术。在每例中，最初的组织学切片显示肿瘤与表皮无连接，这增加了每例均为隐匿性SCC转移灶的可能性。对隐匿性SCC进行仔细检查未发现异常。随后对整个肿瘤进行连续切片，发现4例中有3例肿瘤与上方表皮存在狭窄连接。
