van Iddekinge B, Hofmeyr G J
Department of Obstetrics and Gynaecology, Johannesburg Hospital.
S Afr Med J. 1991 Sep 7;80(5):223-6.
A diagnostic screening programme identified a possible aetiological factor in 32 of 76 couples (42%) evaluated for recurrent spontaneous abortion (three or more consecutive abortions). The abnormalities most commonly observed were endocervical infections (18%), cervical incompetence (11%) and uterine abnormality (9%). Hypothyroidism was present in 3 women and chromosomal abnormality in 2. None were positive for lupus anticoagulant. Treatment of uterine abnormality and cervical incompetence was associated with 75% and 86% success rates, respectively, whereas treatment of infective causes resulted in a 44% successful pregnancy rate, much the same as the 42% rate that occurred in women who had not been thus treated.
一项诊断性筛查项目在对76对因复发性自然流产（连续三次或更多次流产）接受评估的夫妇中的32对（42%）发现了可能的病因。最常观察到的异常情况是宫颈内感染（18%）、宫颈机能不全（11%）和子宫异常（9%）。3名女性存在甲状腺功能减退，2名存在染色体异常。狼疮抗凝物检测均为阴性。子宫异常和宫颈机能不全的治疗成功率分别为75%和86%，而感染性病因的治疗使妊娠成功率达到44%，与未接受此类治疗的女性42%的妊娠成功率大致相同。
