BANG F B
J Exp Med. 1948 Aug;88(2):241-9. doi: 10.1084/jem.88.2.241.
The virus of Newcastle disease of chickens resembles those of the encephalitis group in its ability to spread throughout the developing egg and embryo, but it is similar to influenza virus in the high concentration of it found in the allantoic fluid before death. No effect of the size of the inoculum on the final titer of virus in the allantoic fluid was detected. Good growth occurred at temperatures from 35 degrees to 41 degrees C., apparently more rapid at 40 degrees C. than at 35 degrees C. No appreciable development of virus capable of agglutinating red cells but of low embryo infectivity was found. Although virus multiplication was not immediately perceptible after inoculation, this cannot on present evidence be attributed to a real lag phase.
鸡新城疫病毒在穿透整个发育中的鸡蛋和胚胎的能力方面与脑炎病毒群相似,但在死亡前在尿囊液中发现的高浓度方面与流感病毒相似。未检测到接种量大小对尿囊液中病毒最终滴度的影响。在35摄氏度至41摄氏度的温度下病毒生长良好,显然在40摄氏度时比在35摄氏度时生长得更快。未发现有能凝集红细胞但胚胎感染性低的病毒有明显发育。虽然接种后病毒增殖并非立即可见,但根据目前证据,这不能归因于真正的延迟期。